HitPredict

Interactor 1: PR40A (O75400)
Pre-mRNA-processing factor 40 homolog A (Fas ligand-associated factor 1) (Formin-binding protein 11) (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein 10) (HIP-10) (Huntingtin-interacting protein A) (Renal carcinoma antigen NY-REN-6)
Gene: PRPF40A

Interactor 2: ACINU (Q9UKV3)
Apoptotic chromatin condensation inducer in the nucleus (Acinus)
Gene: ACIN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0016607 - nuclear speck
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 957 Hs			1 1341
+	Hs
		809009 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		ACINU_HUMAN (1-1341): 5.71e-134: 447: 100.00
+	Hs
		263878 PR40A_HUMAN (1-957): 5.9e-97: 328: 100.00		SRRM2_HUMAN (8-1253): 1.08e-39: 163: 10.40
+	Mm
		93578 DESP_MOUSE (362-952): 1.3e-61: 231: 13.30		PLEC_MOUSE (127-1331): 2.49e-66: 250: 12.95
+	Hs
		263765 PR40A_HUMAN (1-957): 5.9e-97: 328: 100.00		PRG4_HUMAN (5-698): 1.32e-23: 111: 9.12
+	Hs
		808624 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		PLEC_HUMAN (127-1331): 9.01e-66: 248: 13.03
+	Dm
		113976 M9PB30_DROME (2-350): 4.07e-23: 108: 10.15		M9PB30_DROME (4-910): 3.12e-61: 234: 10.11
+	Hs
		809056 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		PRC2C_HUMAN (53-1307): 9.8e-44: 177: 8.48
+	Hs
		809031 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		SRRM2_HUMAN (8-1253): 1.08e-39: 163: 10.40
+	Hs
		551790 DESP_HUMAN (419-952): 2.38e-60: 227: 12.98		TITIN_HUMAN (117-1066): 5e-19: 96.4: 11.38
+	Hs
		724839 MYH9_HUMAN (528-957): 1.03e-10: 68.1: 11.11		PLEC_HUMAN (127-1331): 9.01e-66: 248: 13.03
+	Hs
		808598 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		EIF3A_HUMAN (608-1307): 2.15e-25: 116: 9.34
+	Hs
		125817 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		PRC2C_HUMAN (53-1307): 9.8e-44: 177: 8.48
+	Hs
		808785 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		THOC2_HUMAN (949-1336): 6.77e-15: 82.5: 10.47
+	Hs
		125795 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		SRRM2_HUMAN (8-1253): 1.08e-39: 163: 10.40
+	Hs
		152609 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		KMT2D_HUMAN (137-637): 2.21e-12: 74.5: 12.87
+	Hs
		125448 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		EIF3A_HUMAN (608-1307): 2.15e-25: 116: 9.34
+	Dm
		1373179 SUDX_DROME (80-305): 6.98e-18: 91.4: 13.22		Q9VRM6_DROME (1125-1341): 3.99e-17: 89.8: 16.60
+	Dm
		54898 SUDX_DROME (80-305): 6.98e-18: 91.4: 13.22		A1ZA72_DROME (233-1338): 1.97e-09: 64.7: 12.62