HitPredict

Interactor 1: TACC1 (O75410)
Transforming acidic coiled-coil-containing protein 1 (Gastric cancer antigen Ga55) (Taxin-1)
Gene: TACC1

Interactor 2: LYST (Q99698)
Lysosomal-trafficking regulator (Beige homolog)
Gene: LYST

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 805 Hs			1 3801
+	Hs
		1144575 TENS2_HUMAN (31-532): 2.18e-36: 150: 11.71		WDFY3_HUMAN (2955-3744): 1.8e-170: 597: 31.50
+	Hs
		264116 TACC1_HUMAN (1-805): 1.32e-103: 339: 100.00		FBW1B_HUMAN (3301-3799): 6.14e-82: 283: 14.37
+	Hs
		81590 TACC1_HUMAN (1-805): 1.32e-103: 339: 100.00		B7Z3H4_HUMAN (3302-3799): 1.68e-79: 278: 13.75
+	Hs
		264121 TACC1_HUMAN (1-805): 1.32e-103: 339: 100.00		FBW1A_HUMAN (3302-3799): 6.55e-79: 277: 13.75
+	Hs
		3290 TACC1_HUMAN (1-805): 1.32e-103: 339: 100.00		A0A0S2Z507_HUMAN (3302-3799): 2e-78: 276: 13.75
+	Hs
		1144649 TENS2_HUMAN (31-532): 2.18e-36: 150: 11.71		FBW1B_HUMAN (3301-3799): 6.14e-82: 283: 14.37
+	Hs
		1144655 TENS2_HUMAN (31-532): 2.18e-36: 150: 11.71		FBW1A_HUMAN (3302-3799): 6.55e-79: 277: 13.75
+	Hs
		903285 CYTSB_HUMAN (69-780): 7.11e-52: 198: 13.92		WDR5_HUMAN (3695-3799): 3.08e-24: 109: 20.00
+	Hs
		903374 KMT2C_HUMAN (5-646): 3.67e-10: 66.1: 7.94		WDR5_HUMAN (3695-3799): 3.08e-24: 109: 20.00
+	Mm
		903669 KMT2C_MOUSE (7-568): 1.12e-09: 64.5: 9.93		WDR5_MOUSE (3695-3799): 3.08e-24: 109: 20.00