HitPredict

Interactor 1: MAF (O75444)
Transcription factor Maf (Proto-oncogene c-Maf) (V-maf musculoaponeurotic fibrosarcoma oncogene homolog)
Gene: MAF

Interactor 2: MAF (O75444)
Transcription factor Maf (Proto-oncogene c-Maf) (V-maf musculoaponeurotic fibrosarcoma oncogene homolog)
Gene: MAF

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.845

The method score is based on:

Property Details
Experiments 12149651, 23661758, 20102225
Identification Methods pull down, fluorescent resonance energy transfer, peptide array
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains bZIP_Maf~bZIP_Maf
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
and 12 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 373
Hs

1 373
+ Hs
+ Hs
+ Hs
+ Mm
+ Ci
+ Hs
+ Mm
+ Hs
+ Ci
+ Hs
+ Nv
+ Hs
+ Nv
+ Nv
+ Dm
+ Dm

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Last updated: 15 Jul 2024