Interactor 1: SAP30 (O75446)
Histone deacetylase complex subunit SAP30 (30 kDa Sin3-associated polypeptide) (Sin3 corepressor complex subunit SAP30) (Sin3-associated polypeptide p30)
Gene: SAP30

Interactor 2: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 0.60 0.759

The method score is based on:

Property Details
Experiments 26496610, 9651585, 10444591, 11784859, 24981860, 33961781, 16820529, 11283269, 9790534, 35271311, 20388487, 9885572, 21258344
Identification Methods affinity chromatography technology, biochemical, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000118 - histone deacetylase complex
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0030336 - negative regulation of cell migration
and 3 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 220
Hs

1 488
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024