Interactor 1: SAP30 (O75446)
Histone deacetylase complex subunit SAP30 (30 kDa Sin3-associated polypeptide) (Sin3 corepressor complex subunit SAP30) (Sin3-associated polypeptide p30)
Gene: SAP30
Interactor 2: SIN3A (Q96ST3)
Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a)
Gene: SIN3A
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 1.00 | 0.986 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26496610, 9651585, 10444591, 11390640, 11784859, 24981860, 33961781, 9702189, 16820529, 11283269, 9790534, 12724404, 12453419, 11118440, 21676866, 21258344 |
| Identification Methods | affinity chromatography technology, pull down, biochemical, x-ray crystallography, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PAH~SAP30_Sin3_bdg |
| Common GO terms | GO:0000118 - histone deacetylase complex GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003677 - DNA binding GO:0003714 - transcription corepressor activity GO:0005634 - nucleus and 5 others more... |
| Homologous interactions | 4 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
