HitPredict

Interactor 1: SAP30 (O75446)
Histone deacetylase complex subunit SAP30 (30 kDa Sin3-associated polypeptide) (Sin3 corepressor complex subunit SAP30) (Sin3-associated polypeptide p30)
Gene: SAP30

Interactor 2: ING2 (Q9H160)
Inhibitor of growth protein 2 (Inhibitor of growth 1-like protein) (ING1Lp) (p32) (p33ING2)
Gene: ING2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

The method score is based on:

Property	Details
Experiments	26496610, 33961781, 28514442, 16387653
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006355 - regulation of DNA-templated transcription and 5 others more... GO:0030336 - negative regulation of cell migration GO:0030512 - negative regulation of transforming growth factor beta receptor signaling pathway GO:0046872 - metal ion binding GO:1902455 - negative regulation of stem cell population maintenance GO:1902459 - positive regulation of stem cell population maintenance
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1	220
Hs

1	280

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024