HitPredict

Interactor 1: E2F6 (O75461)
Transcription factor E2F6 (E2F-6)
Gene: E2F6

Interactor 2: BRDT (Q58F21)
Bromodomain testis-specific protein (Cancer/testis antigen 9) (CT9) (RING3-like protein)
Gene: BRDT

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	23082233
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 281 Hs			1 947
+	Hs
		265651 E2F6_HUMAN (1-281): 2.39e-95: 284: 100.00		BRD3_HUMAN (6-634): 4.42e-99: 328: 46.22
+	Hs
		1050504 TFDP1_HUMAN (4-232): 1.64e-61: 201: 17.72		BRD3_HUMAN (6-634): 4.42e-99: 328: 46.22
+	Hs
		135274 E2F3_HUMAN (7-281): 6.47e-87: 268: 36.10		CBP_HUMAN (8-304): 2.83e-36: 151: 20.46
+	Hs
		963600 E2F1_HUMAN (10-273): 3.43e-85: 263: 35.25		EP300_HUMAN (2-292): 5.1e-37: 153: 19.26
+	Hs
		963657 E2F1_HUMAN (10-273): 3.43e-85: 263: 35.25		CBP_HUMAN (8-304): 2.83e-36: 151: 20.46
+	Mm
		101447 E2F1_MOUSE (6-256): 1.09e-77: 243: 35.47		F8VPR5_MOUSE (8-304): 3.14e-36: 151: 20.46
+	Hs
		631424 E2F2_HUMAN (3-274): 1.57e-92: 282: 37.42		BRD2_HUMAN (225-928): 1.74e-22: 105: 15.23
+	Hs
		963659 E2F1_HUMAN (10-273): 3.43e-85: 263: 35.25		KAT2B_HUMAN (230-375): 4.27e-27: 120: 26.03
+	Hs
		265732 E2F6_HUMAN (1-281): 2.39e-95: 284: 100.00		ZMYD8_HUMAN (19-725): 1.16e-18: 93.7: 12.06
+	Hs
		963658 E2F1_HUMAN (10-273): 3.43e-85: 263: 35.25		KAT2A_HUMAN (230-375): 1.81e-24: 112: 25.34
+	Hs
		244297 E2F1_HUMAN (10-273): 3.43e-85: 263: 35.25		BRD4_HUMAN (8-921): 1.04e-22: 107: 13.12
+	Hs
		998765 E2F4_HUMAN (62-261): 4.28e-67: 216: 34.78		EP300_HUMAN (2-292): 5.1e-37: 153: 19.26
+	Hs
		631401 E2F1_HUMAN (10-273): 3.43e-85: 263: 35.25		BRD2_HUMAN (225-928): 1.74e-22: 105: 15.23
+	Hs
		265674 E2F6_HUMAN (1-281): 2.39e-95: 284: 100.00		PB1_HUMAN (11-161): 1.56e-14: 80.6: 17.83
+	Mm
		1142625 E2F1_MOUSE (6-256): 1.09e-77: 243: 35.47		KAT2A_MOUSE (230-375): 4.78e-24: 110: 25.34
+	Hs
		1050525 TFDP1_HUMAN (4-232): 1.64e-61: 201: 17.72		CBP_HUMAN (8-304): 2.83e-36: 151: 20.46
+	Hs
		1081345 E2F4_HUMAN (62-261): 4.28e-67: 216: 34.78		KAT2A_HUMAN (230-375): 1.81e-24: 112: 25.34
+	Hs
		244498 E2F4_HUMAN (62-261): 4.28e-67: 216: 34.78		BRD4_HUMAN (8-921): 1.04e-22: 107: 13.12