Protein: MPK6
Mitogen-activated protein kinase 6 (AtMPK6) (MAP kinase 6) (EC 2.7.11.24)

Gene: MPK6
Organism: Arabidopsis thaliana
Interactions: 220
UniProt ID: Q39026

Gene Ontology (top 5):
GO:0000302 - response to reactive oxygen species
GO:0004672 - protein kinase activity
GO:0004707 - MAP kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1184024

M2K2
Mitogen-activated protein kinase kinase 2

6

20

Small-scale

0.953

High

306587

P2C25
Probable protein phosphatase 2C 25

4

13

Small-scale

0.913

High

305983

M2K4
Mitogen-activated protein kinase kinase 4

4

20

Small-scale

0.898

High

1183970

M2K6
Mitogen-activated protein kinase kinase 6

4

20

Small-scale

0.896

High

1183309

MPK1
Mitogen-activated protein kinase 1

3

15

Small-scale

0.850

High

1183932

M2K5
Mitogen-activated protein kinase kinase 5

3

20

Small-scale

0.849

High

306344

Y2706
Probable receptor-like protein kinase At2g47060

1

13

Small-scale

0.780

High

1183898

MPK6
Mitogen-activated protein kinase 6

2

18

Small-scale

0.755

High

1183995

OXI1
Serine/threonine-protein kinase OXI1

1

20

Small-scale

0.710

High

1183951

MKP1
Protein-tyrosine-phosphatase MKP1

1

20

Small-scale

0.680

High

1183939

DGK3
Diacylglycerol kinase 3

3

4

High-throughput

0.672

High

1184055

P2C30
Probable protein phosphatase 2C 30

1

12

Small-scale

0.665

High

1184010

MYB41
Transcription factor MYB41

3

20

Small-scale

0.665

High

71931

CERK1
Chitin elicitor receptor kinase 1

1

14

High-throughput

0.647

High

102092

PBL23
Probable serine/threonine-protein kinase PBL23

1

12

High-throughput

0.647

High

102487

F4JN22
non-specific serine/threonine protein kinase

1

19

High-throughput

0.647

High

847311

KSG3
Shaggy-related protein kinase gamma

1

20

High-throughput

0.647

High

847337

MHK
Serine/threonine-protein kinase MHK

1

20

High-throughput

0.647

High

1082055

NEK5
Serine/threonine-protein kinase Nek5

1

20

High-throughput

0.647

High

1182909

KSG6
Shaggy-related protein kinase zeta

1

20

High-throughput

0.647

High

1183430

MPK2
Mitogen-activated protein kinase 2

1

16

High-throughput

0.647

High

1183899

MPK7
Mitogen-activated protein kinase 7

1

18

High-throughput

0.647

High

1183922

PUB33
U-box domain-containing protein 33

1

13

High-throughput

0.647

High

1183943

GRIK1
Serine/threonine-protein kinase GRIK1

1

18

High-throughput

0.647

High

1183987

MPK8
Mitogen-activated protein kinase 8

1

17

High-throughput

0.647

High

1183991

M2K7
Mitogen-activated protein kinase kinase 7

1

20

Small-scale

0.647

High

1183902

MYC2
Transcription factor MYC2

2

10

Small-scale

0.639

High

1183992

SCRM2
Transcription factor SCREAM2

2

10

High-throughput

0.631

High

1183938

EF103
Ethylene-responsive transcription factor 6

2

20

Small-scale

0.622

High

1184019

DUS1B
Dual specificity protein phosphatase 1B

1

20

Small-scale

0.621

High

1184022

U2AFA
Splicing factor U2af small subunit A

1

0

High-throughput

0.614

High

1184028

IMK2
Probably inactive leucine-rich repeat receptor-like protein kinase IMK2

1

0

High-throughput

0.614

High

1183971

EF104
Ethylene-responsive transcription factor ERF104

1

20

Small-scale

0.609

High

235630

HFA4A
Heat stress transcription factor A-4a

1

8

Small-scale

0.586

High

879918

GBB
Guanine nucleotide-binding protein subunit beta

1

7

Small-scale

0.586

High

1183942

Q8W569
AT4g26650/T15N24_100

1

14

High-throughput

0.579

High

1183953

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

10

High-throughput

0.579

High

1184042

CML38
Calcium-binding protein CML38

1

11

High-throughput

0.579

High

1183917

Q84JD1
START

2

5

High-throughput

0.576

High

1183979

M2K9
Mitogen-activated protein kinase kinase 9

1

20

Small-scale

0.575

High

200965

GBLPA
Small ribosomal subunit protein RACK1z

1

17

Small-scale

0.561

High

1183967

EB1C
Microtubule-associated protein RP/EB family member 1C

1

4

Small-scale

0.561

High

535755

NIA2
Nitrate reductase [NADH] 2

1

6

Small-scale

0.559

High

1183949

ZAT10
Zinc finger protein ZAT10

1

2

Small-scale

0.549

High

1184053

LIP5
Protein HOMOLOG OF MAMMALIAN LYST-INTERACTING PROTEIN 5

1

2

Small-scale

0.543

High

199060

O22691
At1g04330

1

1

High-throughput

0.541

High

1183988

BZR2
Protein BRASSINAZOLE-RESISTANT 2

1

1

Small-scale

0.536

High

800407

TBG1
Tubulin gamma-1 chain

1

18

Small-scale

0.536

High

198943

ZAT6
Zinc finger protein ZAT6

1

3

Small-scale

0.527

High

549366

NIA1
Nitrate reductase [NADH] 1

1

5

Small-scale

0.527

High

1184017

WSD4
Wax ester synthase/diacylglycerol acyltransferase 4

1

0

High-throughput

0.518

High

265662

NDK2
Nucleoside diphosphate kinase II, chloroplastic

1

6

Small-scale

0.508

High

49253

ABI4
Ethylene-responsive transcription factor ABI4

1

20

High-throughput

0.501

High

75231

RVE7
Protein REVEILLE 7

1

20

High-throughput

0.501

High

90466

BBX19
B-box zinc finger protein 19

1

9

High-throughput

0.501

High

100420

TRB4
Telomere repeat-binding factor 4

1

5

High-throughput

0.501

High

100558

F4I9R1
Basic-leucine zipper

1

14

High-throughput

0.501

High

101172

MYB88
Transcription factor MYB88

1

20

High-throughput

0.501

High

101539

F4J1R5
Myb domain protein 110

1

20

High-throughput

0.501

High

101576

F4J2X8
Myb domain protein 15

1

20

High-throughput

0.501

High

102278

TCX2
Protein tesmin/TSO1-like CXC 2

1

3

High-throughput

0.501

High

103855

RVE1
Protein REVEILLE 1

1

20

High-throughput

0.501

High

199405

WRK23
WRKY transcription factor 23

1

20

High-throughput

0.501

High

200022

SCL15
Scarecrow-like protein 15

1

20

High-throughput

0.501

High

308377

BBX23
B-box zinc finger protein 23

1

9

High-throughput

0.501

High

711979

AGL1
Agamous-like MADS-box protein AGL1

1

8

High-throughput

0.501

High

749558

IAA5
Auxin-responsive protein IAA5

1

15

High-throughput

0.501

High

774836

AP1
Floral homeotic protein APETALA 1

1

6

High-throughput

0.501

High

868635

AP2
Floral homeotic protein APETALA 2

1

20

High-throughput

0.501

High

873818

TF2B1
Transcription initiation factor IIB-1

1

8

High-throughput

0.501

High

963634

DRE2G
Dehydration-responsive element-binding protein 2G

1

20

High-throughput

0.501

High

1020091

CDC5L
Cell division cycle 5-like protein

1

20

High-throughput

0.501

High

1020812

DRE1B
Dehydration-responsive element-binding protein 1B

1

20

High-throughput

0.501

High

1045013

POF21
Probable transcription factor PosF21

1

13

High-throughput

0.501

High

1177264

Q29PT3
At3g49760

1

12

High-throughput

0.501

High

1181982

IAA11
Auxin-responsive protein IAA11

1

13

High-throughput

0.501

High

1182110

AGL11
Agamous-like MADS-box protein AGL11

1

8

High-throughput

0.501

High

1182214

AGL15
Agamous-like MADS-box protein AGL15

1

17

High-throughput

0.501

High

1182247

MYB6
Transcription repressor MYB6

1

20

High-throughput

0.501

High

1183900

CONS
Zinc finger protein CONSTANS

1

9

High-throughput

0.501

High

1183901

TGA6
Transcription factor TGA6

1

7

High-throughput

0.501

High

1183903

TGA1
Transcription factor TGA1

1

7

High-throughput

0.501

High

1183904

SKP1A
SKP1-like protein 1A

1

7

High-throughput

0.501

High

1183905

ZFP4
Zinc finger protein 4

1

3

High-throughput

0.501

High

1183906

Q4PSE3
AGAMOUS-like 101

1

20

High-throughput

0.501

High

1183907

BZP16
bZIP transcription factor 16

1

14

High-throughput

0.501

High

1183908

AIL6
AP2-like ethylene-responsive transcription factor AIL6

1

20

High-throughput

0.501

High

1183909

JMJ20
Arginine-specific demethylase JMJ20

1

6

High-throughput

0.501

High

1183911

MB3R5
Transcription factor MYB3R-5

1

20

High-throughput

0.501

High

1183912

MYB63
Transcription factor MYB63

1

20

High-throughput

0.501

High

1183913

RVE4
Protein REVEILLE 4

1

20

High-throughput

0.501

High

1183914

RVE3
Protein REVEILLE 3

1

20

High-throughput

0.501

High

1183916

AGL53
Agamous-like MADS-box protein AGL53

1

20

High-throughput

0.501

High

1183918

DOF18
Dof zinc finger protein DOF1.8

1

20

High-throughput

0.501

High

1183919

SUFE1
SufE-like protein 1, chloroplastic/mitochondrial

1

2

High-throughput

0.501

High

1183921

GTE1
Transcription factor GTE1

1

12

High-throughput

0.501

High

1183924

GAT24
GATA transcription factor 24

1

8

High-throughput

0.501

High

1183925

Q8GYQ9
Enhancer of polycomb-like protein

1

5

High-throughput

0.501

High

1183926

IAA31
Auxin-responsive protein IAA31

1

13

High-throughput

0.501

High

1183927

TCP4
Transcription factor TCP4

1

7

High-throughput

0.501

High

1183929

JMJ30
Lysine-specific demethylase JMJ30

1

6

High-throughput

0.501

High

1183931

RVE8
Protein REVEILLE 8

1

20

High-throughput

0.501

High

1183933

Q8RXU8
MYB transcription factor

1

11

High-throughput

0.501

High

1183934

ATB17
Homeobox-leucine zipper protein ATHB-17

1

13

High-throughput

0.501

High

1183935

WRK61
Probable WRKY transcription factor 61

1

20

High-throughput

0.501

High

1183936

MSRB7
Peptide methionine sulfoxide reductase B7

1

5

High-throughput

0.501

High

1183937

PHO32
Universal stress protein PHOS32

1

2

Small-scale

0.501

High

1183941

BH012
Transcription factor MYC1

1

11

High-throughput

0.501

High

1183944

WRK58
Probable WRKY transcription factor 58

1

20

High-throughput

0.501

High

1183945

WRK69
Probable WRKY transcription factor 69

1

20

High-throughput

0.501

High

1183946

KAN3
Probable transcription factor KAN3

1

20

High-throughput

0.501

High

1183947

PFKA3
ATP-dependent 6-phosphofructokinase 3

1

10

High-throughput

0.501

High

1183948

Q94GA6
MYB transcription factor

1

20

High-throughput

0.501

High

1183950

GPLPB
Small ribosomal subunit protein RACK1y

1

14

Small-scale

0.501

High

1183952

ARFR
Auxin response factor 18

1

13

High-throughput

0.501

High

1183955

DF1
Trihelix transcription factor DF1

1

17

High-throughput

0.501

High

1183956

MYB20
Transcription factor MYB20

1

20

High-throughput

0.501

High

1183957

BH080
Transcription factor bHLH80

1

14

High-throughput

0.501

High

1183958

Q9C9D4
At1g72350

1

17

High-throughput

0.501

High

1183960

SCL28
Scarecrow-like protein 28

1

20

High-throughput

0.501

High

1183961

WRK36
Probable WRKY transcription factor 36

1

20

High-throughput

0.501

High

1183962

HFR1
Transcription factor HFR1

1

9

High-throughput

0.501

High

1183963

Q9FF65
At5g05090

1

20

High-throughput

0.501

High

1183965

ALFL1
PHD finger protein ALFIN-LIKE 1

1

8

High-throughput

0.501

High

1183968

ERF25
Ethylene-responsive transcription factor ERF025

1

20

High-throughput

0.501

High

1183969

Q9FJS9
At5g56840

1

20

High-throughput

0.501

High

1183972

Q9FL19
AGAMOUS-like 76

1

20

High-throughput

0.501

High

1183973

AGL75
Agamous-like MADS-box protein AGL75

1

20

High-throughput

0.501

High

1183974

TCP7
Transcription factor TCP7

1

15

High-throughput

0.501

High

1183976

SRM1
Transcription factor SRM1

1

20

High-throughput

0.501

High

1183977

HHO3
Transcription factor HHO3

1

14

High-throughput

0.501

High

1183980

HHO6
Transcription factor HHO6

1

12

High-throughput

0.501

High

1183981

SRS7
Protein SHI RELATED SEQUENCE 7

1

5

High-throughput

0.501

High

1183982

MYB64
Transcription factor MYB64

1

20

High-throughput

0.501

High

1183983

WRK75
Probable WRKY transcription factor 75

1

20

High-throughput

0.501

High

1183984

FLOR1
Leucine-rich repeat protein FLOR 1

1

1

High-throughput

0.501

High

1183985

MYB21
Transcription factor MYB21

1

20

High-throughput

0.501

High

1183986

RBR1
Retinoblastoma-related protein 1

1

7

High-throughput

0.501

High

1183989

ERF94
Ethylene-responsive transcription factor ERF094

1

20

High-throughput

0.501

High

1183990

ETC1
MYB-like transcription factor ETC1

1

20

High-throughput

0.501

High

1183993

DRE2D
Dehydration-responsive element-binding protein 2D

1

20

High-throughput

0.501

High

1183994

ICE1
Transcription factor ICE1

1

15

High-throughput

0.501

High

1183996

MYB35
Transcription factor MYB35

1

20

High-throughput

0.501

High

1183997

PCLL
Transcription factor BOA

1

18

High-throughput

0.501

High

1183998

ERF36
Ethylene-responsive transcription factor ERF036

1

20

High-throughput

0.501

High

1183999

GPLPC
Small ribosomal subunit protein RACK1x

1

14

Small-scale

0.501

High

1184000

TOE2
AP2-like ethylene-responsive transcription factor TOE2

1

20

High-throughput

0.501

High

1184001

HSFA9
Heat stress transcription factor A-9

1

8

High-throughput

0.501

High

1184002

MYB48
Transcription factor MYB48

1

20

High-throughput

0.501

High

1184003

HEC3
Transcription factor HEC3

1

20

High-throughput

0.501

High

1184004

WRK72
Probable WRKY transcription factor 72

1

20

High-throughput

0.501

High

1184005

EF115
Ethylene-responsive transcription factor ERF115

1

20

High-throughput

0.501

High

1184006

Q9LY95
MYB transcription factor

1

20

High-throughput

0.501

High

1184007

WRK62
Probable WRKY transcription factor 62

1

20

High-throughput

0.501

High

1184008

PFKA6
ATP-dependent 6-phosphofructokinase 6

1

10

High-throughput

0.501

High

1184011

LAF1
Transcription factor LAF1

1

20

High-throughput

0.501

High

1184012

DRE1A
Dehydration-responsive element-binding protein 1A

1

20

High-throughput

0.501

High

1184013

BH081
Transcription factor bHLH81

1

12

High-throughput

0.501

High

1184014

Q9M118
Myb domain protein 55

1

20

High-throughput

0.501

High

1184015

DOF32
Dof zinc finger protein DOF3.2

1

20

High-throughput

0.501

High

1184016

RAX3
Transcription factor RAX3

1

20

High-throughput

0.501

High

1184020

WRK66
Probable WRKY transcription factor 66

1

20

High-throughput

0.501

High

1184021

TCP3
Transcription factor TCP3

1

7

High-throughput

0.501

High

1184023

FLC
MADS-box protein FLOWERING LOCUS C

1

10

High-throughput

0.501

High

1184025

MYB93
Transcription factor MYB93

1

20

High-throughput

0.501

High

1184026

AHP3
Histidine-containing phosphotransfer protein 3

1

5

High-throughput

0.501

High

1184027

MYB92
Transcription factor MYB92

1

20

High-throughput

0.501

High

1184029

WER
Transcription factor WER

1

20

High-throughput

0.501

High

1184030

WRK55
WRKY transcription factor 55

1

20

High-throughput

0.501

High

1184031

SCRK1
Probable fructokinase-1

1

8

High-throughput

0.501

High

1184032

MYB14
Transcription factor MYB14

1

20

High-throughput

0.501

High

1184033

ARFJ
Auxin response factor 10

1

13

High-throughput

0.501

High

1184034

ERF55
Ethylene-responsive transcription factor ERF055

1

20

High-throughput

0.501

High

1184035

Q9SLH1
Myb domain protein 81

1

20

High-throughput

0.501

High

1184036

NFYC1
Nuclear transcription factor Y subunit C-1

1

15

High-throughput

0.501

High

1184037

MYB94
Transcription factor MYB94

1

20

High-throughput

0.501

High

1184038

ERF11
Ethylene-responsive transcription factor ERF011

1

20

High-throughput

0.501

High

1184039

MYB26
Transcription factor MYB26

1

20

High-throughput

0.501

High

1184040

WRK39
Probable WRKY transcription factor 39

1

20

High-throughput

0.501

High

1184041

Q9SRB0
MYB transcription factor

1

20

High-throughput

0.501

High

1184043

LEA2
Late embryogenis abundant protein 2

1

3

High-throughput

0.501

High

1184044

TF2B2
Transcription initiation factor IIB-2

1

8

High-throughput

0.501

High

1184045

SINA4
E3 ubiquitin-protein ligase SINAT4

1

8

High-throughput

0.501

High

1184046

WRKY7
Probable WRKY transcription factor 7

1

20

High-throughput

0.501

High

1184047

ERLL1
pEARLI1-like lipid transfer protein 1

1

1

Small-scale

0.501

High

1184049

WRK53
Probable WRKY transcription factor 53

1

20

High-throughput

0.501

High

1184050

Q9SUT6
AGAMOUS-like 52

1

20

High-throughput

0.501

High

1184051

NFYA5
Nuclear transcription factor Y subunit A-5

1

10

High-throughput

0.501

High

1184052

EF109
Ethylene-responsive transcription factor ERF109

1

20

High-throughput

0.501

High

1184054

Q9T0G9
Myb domain protein 79

1

20

High-throughput

0.501

High

1184056

Q9XIE7
AGAMOUS-like 50

1

11

High-throughput

0.501

High

1184057

WRKY3
Probable WRKY transcription factor 3

1

18

High-throughput

0.501

High

1184058

MSRB5
Peptide methionine sulfoxide reductase B5

1

5

High-throughput

0.501

High

308424

PTP1
Protein-tyrosine-phosphatase PTP1

1

16

Small-scale

0.481

High

1183940

SWC4
SWR1-complex protein 4

1

0

High-throughput

0.480

High

1183954

PINI
Auxin efflux carrier component 1

1

0

Small-scale

0.480

High

1183964

MBS2
Protein METHYLENE BLUE SENSITIVITY 2

1

0

High-throughput

0.480

High

70583

A8MQF2
Alpha/beta-Hydrolases superfamily protein

1

6

High-throughput

0.457

High

100533

F4I9C1
Hydroxyproline-rich glycoprotein family protein

1

4

High-throughput

0.457

High

265908

CRK9
Putative cysteine-rich receptor-like protein kinase 9

1

5

High-throughput

0.457

High

307289

LBD31
LOB domain-containing protein 31

1

20

High-throughput

0.457

High

307293

LBD30
LOB domain-containing protein 30

1

20

High-throughput

0.457

High

1183910

Q6ID73
At2g26695

1

11

High-throughput

0.457

High

1183915

AL3F1
Aldehyde dehydrogenase family 3 member F1

1

3

High-throughput

0.457

High

1183923

Q8GUJ6
At4g28530

1

15

High-throughput

0.457

High

1183928

Q8RWE1
Metallo-beta-lactamase family protein

1

6

High-throughput

0.457

High

1183930

Q8RWR9
Uncharacterized protein At5g42070

1

3

High-throughput

0.457

High

1183959

Y1385
BTB/POZ domain-containing protein At1g63850

1

1

High-throughput

0.457

High

1183966

Q9FFX5
At5g14000

1

16

High-throughput

0.457

High

1183975

LBD37
LOB domain-containing protein 37

1

20

High-throughput

0.457

High

1183978

Q9FWT4
ATP-dependent protease La

1

4

High-throughput

0.457

High

1184009

C3H49
Zinc finger CCCH domain-containing protein 49

1

4

High-throughput

0.457

High

1184018

LBD41
LOB domain-containing protein 41

1

20

High-throughput

0.457

High

199420

WRK25
Probable WRKY transcription factor 25

1

19

Small-scale

0.445

High

99816

F4HYN6
DUF7650 domain-containing protein

1

0

High-throughput

0.261

Low

102079

F4JEH8
Histone H2A deubiquitinase

1

0

High-throughput

0.261

Low

103738

F4KB54
DDT domain-containing protein

1

0

High-throughput

0.261

Low

1183920

Q84WW4
RING finger family protein

1

0

High-throughput

0.261

Low

1184048

Q9SU83
Alkaline-phosphatase-like family protein

1

0

High-throughput

0.261

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025