HitPredict

Interactor 1: PSIP1 (O75475)
PC4 and SFRS1-interacting protein (CLL-associated antigen KW-7) (Dense fine speckles 70 kDa protein) (DFS 70) (Lens epithelium-derived growth factor) (Transcriptional coactivator p75/p52)
Gene: PSIP1

Interactor 2: CBX3 (Q13185)
Chromobox protein homolog 3 (HECH) (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein)
Gene: CBX3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000791 - euchromatin GO:0000792 - heterochromatin GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm and 1 others more... GO:0006338 - chromatin remodeling
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 530 Hs			1 183
+	Hs
		1027243 NSD3_HUMAN (4-445): 6.35e-74: 257: 14.91		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		1027195 NSD1_HUMAN (2-529): 5.98e-69: 243: 11.41		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		1317731 NSD3_HUMAN (4-445): 6.35e-74: 257: 14.91		V9HWG0_HUMAN (11-182): 1.62e-55: 175: 59.89
+	Hs
		800517 NSD3_HUMAN (4-445): 6.35e-74: 257: 14.91		CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89
+	Hs
		265992 PSIP1_HUMAN (1-530): 1.2e-79: 260: 100.00		CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33
+	Hs
		949878 NSD3_HUMAN (4-445): 6.35e-74: 257: 14.91		CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33
+	Hs
		331801 NSD2_HUMAN (3-444): 2.88e-58: 211: 13.09		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Mm
		1265741 GLYR1_MOUSE (4-205): 1.09e-36: 144: 20.98		Q9DCC5_MOUSE (1-183): 1.62e-71: 215: 100.00
+	Dm
		399008 ZMYD8_DROME (10-467): 1.33e-50: 189: 12.21		HP1_DROME (9-180): 2.12e-45: 150: 38.73
+	Mm
		1143040 GLYR1_MOUSE (4-205): 1.09e-36: 144: 20.98		CBX5_MOUSE (11-182): 1.21e-55: 175: 59.89
+	Hs
		850916 HDGF_HUMAN (3-225): 5.03e-24: 102: 38.94		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		1027088 HDGR2_HUMAN (1-521): 2.98e-21: 99.5: 20.73		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Mm
		949958 GLYR1_MOUSE (4-205): 1.09e-36: 144: 20.98		CBX1_MOUSE (36-180): 1.02e-53: 170: 71.33
+	Hs
		1027327 ZMYD8_HUMAN (10-490): 5.97e-17: 86.4: 13.32		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		949825 HDGR2_HUMAN (1-521): 2.98e-21: 99.5: 20.73		CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33
+	Mm
		291745 DNM3B_MOUSE (3-196): 2.47e-11: 68.3: 11.17		CBX2_MOUSE (20-117): 6.27e-26: 104: 27.00