Interactor 1: NDUS3 (O75489)
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (EC 7.1.1.2) (Complex I-30kD) (CI-30kD) (NADH-ubiquinone oxidoreductase 30 kDa subunit)
Gene: NDUFS3

Interactor 2: NDUA5 (Q16718)
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (Complex I subunit B13) (Complex I-13kD-B) (CI-13kD-B) (NADH-ubiquinone oxidoreductase 13 kDa-B subunit)
Gene: NDUFA5

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.965

The method score is based on:

Property Details
Experiments 26186194, 24344204, 27499296, 28514442, 33961781, 32296183, unassigned1304
Identification Methods affinity chromatography technology, two hybrid, two hybrid prey pooling approach, two hybrid array, anti tag coimmunoprecipitation, validated two hybrid
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Complex1_30kDa~ETC_C1_NDUFA5
Common GO terms GO:0005743 - mitochondrial inner membrane
GO:0006120 - mitochondrial electron transport, NADH to ubiquinone
GO:0008137 - NADH dehydrogenase (ubiquinone) activity
GO:0009060 - aerobic respiration
GO:0032981 - mitochondrial respiratory chain complex I assembly
and 1 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 264
Hs

1 116
+ Dm

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Last updated: 15 Jul 2024