HitPredict

Interactor 1: SRS10 (O75494)
Serine/arginine-rich splicing factor 10 (40 kDa SR-repressor protein) (SRrp40) (FUS-interacting serine-arginine-rich protein 1) (Splicing factor SRp38) (Splicing factor, arginine/serine-rich 13A) (TLS-associated protein with Ser-Arg repeats) (TASR) (TLS-associated protein with SR repeats) (TLS-associated serine-arginine protein) (TLS-associated SR protein)
Gene: SRSF10

Interactor 2: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.60	0.711

Property	Details
Experiments	33961781, 36931259, 15324660, 17353931, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, split luciferase complementation, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 262 Hs			1 247
+	Hs
		904922 SRS12_HUMAN (1-251): 1.31e-38: 137: 46.33		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		266952 SRS10_HUMAN (1-262): 2.41e-34: 126: 100.00		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		982334 SRS12_HUMAN (1-251): 1.31e-38: 137: 46.33		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Hs
		910157 PPIE_HUMAN (10-98): 5.42e-30: 115: 31.46		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		266969 SRS10_HUMAN (1-262): 2.41e-34: 126: 100.00		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Hs
		905260 PPIE_HUMAN (10-98): 5.42e-30: 115: 31.46		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		909453 SRSF2_HUMAN (4-90): 1.89e-24: 99.3: 45.65		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		904441 SRSF3_HUMAN (1-95): 1.17e-25: 100: 35.79		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		683581 SRS12_HUMAN (1-251): 1.31e-38: 137: 46.33		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		266918 SRS10_HUMAN (1-262): 2.41e-34: 126: 100.00		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		647148 SRS12_HUMAN (1-251): 1.31e-38: 137: 46.33		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		266959 SRS10_HUMAN (1-262): 2.41e-34: 126: 100.00		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		683812 PPIE_HUMAN (10-98): 5.42e-30: 115: 31.46		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		266915 SRS10_HUMAN (1-262): 2.41e-34: 126: 100.00		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		927658 PPIE_HUMAN (10-98): 5.42e-30: 115: 31.46		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		683264 SRSF3_HUMAN (1-95): 1.17e-25: 100: 35.79		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		266919 SRS10_HUMAN (1-262): 2.41e-34: 126: 100.00		1433S_HUMAN (2-245): 1.86e-98: 289: 65.16
+	Hs
		646795 SRSF3_HUMAN (1-95): 1.17e-25: 100: 35.79		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		684394 PPIE_HUMAN (10-98): 5.42e-30: 115: 31.46		1433S_HUMAN (2-245): 1.86e-98: 289: 65.16
+	Hs
		683970 SRSF2_HUMAN (4-90): 1.89e-24: 99.3: 45.65		1433S_HUMAN (2-245): 1.86e-98: 289: 65.16