HitPredict

Interactor 1: SRS10 (O75494)
Serine/arginine-rich splicing factor 10 (40 kDa SR-repressor protein) (SRrp40) (FUS-interacting serine-arginine-rich protein 1) (Splicing factor SRp38) (Splicing factor, arginine/serine-rich 13A) (TLS-associated protein with Ser-Arg repeats) (TASR) (TLS-associated protein with SR repeats) (TLS-associated serine-arginine protein) (TLS-associated SR protein)
Gene: SRSF10

Interactor 2: PININ (Q9H307)
Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Desmosome-associated protein) (Domain-rich serine protein) (DRS protein) (DRSP) (Melanoma metastasis clone A protein) (Nuclear protein SDK3) (SR-like protein)
Gene: PNN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0016607 - nuclear speck
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 262 Hs			1 717
+	Hs
		1329876 PPIE_HUMAN (10-98): 5.42e-30: 115: 31.46		PININ_HUMAN (1-717): 3.37e-144: 440: 100.00
+	Hs
		952121 SRSF3_HUMAN (1-95): 1.17e-25: 100: 35.79		PININ_HUMAN (1-717): 3.37e-144: 440: 100.00
+	Hs
		1031460 PABP4_HUMAN (2-99): 3.59e-20: 91.3: 18.37		PININ_HUMAN (1-717): 3.37e-144: 440: 100.00