HitPredict

Interactor 1: SRS10 (O75494)
Serine/arginine-rich splicing factor 10 (40 kDa SR-repressor protein) (SRrp40) (FUS-interacting serine-arginine-rich protein 1) (Splicing factor SRp38) (Splicing factor, arginine/serine-rich 13A) (TLS-associated protein with Ser-Arg repeats) (TASR) (TLS-associated protein with SR repeats) (TLS-associated serine-arginine protein) (TLS-associated SR protein)
Gene: SRSF10

Interactor 2: FBW1A (Q9Y297)
F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit)
Gene: BTRC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36199071
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 262 Hs			1 605
+	Hs
		952182 SRSF3_HUMAN (1-95): 1.17e-25: 100: 35.79		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Hs
		1031501 PABP4_HUMAN (2-99): 3.59e-20: 91.3: 18.37		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Hs
		516754 PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Hs
		1031492 PABP4_HUMAN (2-99): 3.59e-20: 91.3: 18.37		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		516733 PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		267038 SRS10_HUMAN (1-262): 2.41e-34: 126: 100.00		FBXW7_HUMAN (76-527): 7.38e-83: 276: 23.71
+	Hs
		964042 SRSF2_HUMAN (4-90): 1.89e-24: 99.3: 45.65		FBXW7_HUMAN (76-527): 7.38e-83: 276: 23.71
+	Hs
		266949 SRS10_HUMAN (1-262): 2.41e-34: 126: 100.00		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33
+	Hs
		209499 PPIE_HUMAN (10-98): 5.42e-30: 115: 31.46		PLRG1_HUMAN (417-604): 2.83e-38: 150: 23.47
+	Hs
		952150 SRSF3_HUMAN (1-95): 1.17e-25: 100: 35.79		NLE1_HUMAN (33-408): 1.35e-41: 159: 13.21
+	Hs
		964033 SRSF2_HUMAN (4-90): 1.89e-24: 99.3: 45.65		POC1B_HUMAN (189-438): 4.67e-35: 140: 13.27
+	Hs
		903196 PABP4_HUMAN (2-99): 3.59e-20: 91.3: 18.37		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33
+	Hs
		516438 PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33