Protein: VDAC3
Non-selective voltage-gated ion channel VDAC3 (VDAC-3) (hVDAC3) (Outer mitochondrial membrane protein porin 3)

Gene: VDAC3
Organism: Homo sapiens
Interactions: 176
UniProt ID: Q9Y277

Gene Ontology (top 5):
GO:0000166 - nucleotide binding
GO:0001662 - behavioral fear response
GO:0005244 - voltage-gated monoatomic ion channel activity
GO:0005634 - nucleus
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

641067

VDAC1
Non-selective voltage-gated ion channel VDAC1

5

9

High-throughput

0.925

High

852887

VDAC2
Non-selective voltage-gated ion channel VDAC2

3

9

High-throughput

0.855

High

243322

PRKN
E3 ubiquitin-protein ligase parkin

4

6

Small-scale

0.676

High

387480

APOE
Apolipoprotein E

2

1

High-throughput

0.628

High

557537

SRC
Proto-oncogene tyrosine-protein kinase Src

2

1

High-throughput

0.628

High

878112

AGRE5
Adhesion G protein-coupled receptor E5

2

1

High-throughput

0.628

High

1279273

SPT19
Spermatogenesis-associated protein 19, mitochondrial

2

0

High-throughput

0.602

High

423484

A4
Amyloid-beta precursor protein

2

4

Small-scale

0.601

High

508855

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

2

5

Small-scale

0.584

High

809923

RS19
Small ribosomal subunit protein eS19

2

2

High-throughput

0.584

High

831671

CCNF
Cyclin-F

2

3

High-throughput

0.584

High

1380265

FBXW7
F-box/WD repeat-containing protein 7

2

3

Small-scale

0.584

High

861846

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

6

Small-scale

0.578

High

375025

RASH
GTPase HRas

2

9

High-throughput

0.574

High

397254

ESR1
Estrogen receptor

2

7

High-throughput

0.571

High

1391082

OTUB1
Ubiquitin thioesterase OTUB1

2

1

High-throughput

0.571

High

1428593

DDX24
ATP-dependent RNA helicase DDX24

1

2

High-throughput

0.541

High

583616

ATF2
Cyclic AMP-dependent transcription factor ATF-2

1

4

High-throughput

0.536

High

605854

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

5

High-throughput

0.536

High

621546

HXK1
Hexokinase-1

1

7

High-throughput

0.536

High

690430

STOM
Stomatin

1

9

High-throughput

0.536

High

774014

SOAT1
Sterol O-acyltransferase 1

1

3

High-throughput

0.536

High

914138

HXK2
Hexokinase-2

1

7

High-throughput

0.536

High

956546

RAB2A
Ras-related protein Rab-2A

1

13

High-throughput

0.536

High

981384

RAB1A
Ras-related protein Rab-1A

1

10

High-throughput

0.536

High

1098771

NDK3
Nucleoside diphosphate kinase 3

1

3

High-throughput

0.536

High

1101106

G3BP1
Ras GTPase-activating protein-binding protein 1

1

6

High-throughput

0.536

High

1123479

ICT1
Large ribosomal subunit protein mL62

1

1

High-throughput

0.536

High

1125738

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

7

High-throughput

0.536

High

1270675

COX15
Heme A synthase COX15

1

3

High-throughput

0.536

High

1431920

S38A1
Sodium-coupled neutral amino acid symporter 1

1

1

High-throughput

0.536

High

885722

CASP4
Caspase-4

1

1

High-throughput

0.515

High

1217230

RIF1
Telomere-associated protein RIF1

1

6

High-throughput

0.515

High

1415956

HIRP3
HIRA-interacting protein 3

1

1

High-throughput

0.515

High

664916

RAE1
Rab proteins geranylgeranyltransferase component A 1

1

0

High-throughput

0.513

High

932013

EPHB4
Ephrin type-B receptor 4

1

1

High-throughput

0.500

High

1416963

KLF16
Krueppel-like factor 16

1

6

High-throughput

0.500

High

1292992

ZN227
Zinc finger protein 227

1

0

High-throughput

0.493

High

184244

RER1
Protein RER1

1

1

High-throughput

0.489

High

518637

RAP2A
Ras-related protein Rap-2a

1

15

High-throughput

0.489

High

1142222

P2RY6
P2Y purinoceptor 6

1

7

High-throughput

0.489

High

1152304

MARE1
Microtubule-associated protein RP/EB family member 1

1

1

High-throughput

0.489

High

1386418

FAF2
FAS-associated factor 2

1

7

High-throughput

0.489

High

1431014

UN93B
Protein unc-93 homolog B1

1

4

High-throughput

0.489

High

1462233

G3BP2
Ras GTPase-activating protein-binding protein 2

1

8

High-throughput

0.489

High

74648

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

6

High-throughput

0.479

High

85539

HNRC3
Heterogeneous nuclear ribonucleoprotein C-like 3

1

6

High-throughput

0.479

High

106876

APRIO
Alternative prion protein

1

2

High-throughput

0.479

High

125669

LEG9
Galectin-9

1

1

High-throughput

0.479

High

189038

TMPS2
Transmembrane protease serine 2

1

11

High-throughput

0.479

High

223433

PRC1
Protein regulator of cytokinesis 1

1

3

High-throughput

0.479

High

227714

SPOP
Speckle-type POZ protein

1

1

High-throughput

0.479

High

256705

HNRC1
Heterogeneous nuclear ribonucleoprotein C-like 1

1

6

High-throughput

0.479

High

320157

UFL1
E3 UFM1-protein ligase 1

1

2

High-throughput

0.479

High

331432

KI20A
Kinesin-like protein KIF20A

1

9

High-throughput

0.479

High

350186

SNAI1
Zinc finger protein SNAI1

1

1

High-throughput

0.479

High

352601

TOP3B
DNA topoisomerase 3-beta-1

1

2

High-throughput

0.479

High

373533

MYC
Myc proto-oncogene protein

1

3

High-throughput

0.479

High

380196

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

2

High-throughput

0.479

High

401721

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

4

High-throughput

0.479

High

412835

NTRK1
High affinity nerve growth factor receptor

1

7

High-throughput

0.479

High

459352

CATL1
Procathepsin L

1

2

High-throughput

0.479

High

462716

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

6

High-throughput

0.479

High

551343

PCNA
Proliferating cell nuclear antigen

1

2

High-throughput

0.479

High

558509

XRCC6
X-ray repair cross-complementing protein 6

1

4

High-throughput

0.479

High

590066

RFA2
Replication protein A 32 kDa subunit

1

3

High-throughput

0.479

High

693140

DPP4
Dipeptidyl peptidase 4

1

2

High-throughput

0.479

High

696900

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.479

High

774715

BASI
Basigin

1

2

High-throughput

0.479

High

800176

COIL
Coilin

1

2

High-throughput

0.479

High

848451

MAGA6
Melanoma-associated antigen 6

1

3

High-throughput

0.479

High

879632

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

2

High-throughput

0.479

High

905303

MECP2
Methyl-CpG-binding protein 2

1

3

High-throughput

0.479

High

907631

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

4

High-throughput

0.479

High

930086

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

2

High-throughput

0.479

High

939989

TPTE
Putative tyrosine-protein phosphatase TPTE

1

1

High-throughput

0.479

High

959299

ABCE1
ATP-binding cassette sub-family E member 1

1

1

High-throughput

0.479

High

965342

WDR5
WD repeat-containing protein 5

1

3

High-throughput

0.479

High

984338

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

3

High-throughput

0.479

High

986825

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

3

High-throughput

0.479

High

1062724

DHX9
ATP-dependent RNA helicase A

1

2

Small-scale

0.479

High

1068340

AHNK
Neuroblast differentiation-associated protein AHNAK

1

4

High-throughput

0.479

High

1088625

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

4

High-throughput

0.479

High

1107347

BIRC3
Baculoviral IAP repeat-containing protein 3

1

3

High-throughput

0.479

High

1109439

SERC3
Serine incorporator 3

1

1

High-throughput

0.479

High

1121377

TRI14
Tripartite motif-containing protein 14

1

1

High-throughput

0.479

High

1122591

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

5

High-throughput

0.479

High

1141061

KIF14
Kinesin-like protein KIF14

1

4

High-throughput

0.479

High

1161086

FSCN1
Fascin

1

1

High-throughput

0.479

High

1197758

MIDN
Midnolin

1

3

High-throughput

0.479

High

1229776

VIR
Protein virilizer homolog

1

2

High-throughput

0.479

High

1286959

TM11B
Transmembrane protease serine 11B

1

10

High-throughput

0.479

High

1289734

NAA40
N-alpha-acetyltransferase 40

1

2

High-throughput

0.479

High

1313545

SMC5
Structural maintenance of chromosomes protein 5

1

3

High-throughput

0.479

High

1367621

ESR2
Estrogen receptor beta

1

7

High-throughput

0.479

High

1397572

CI072
Guanine nucleotide exchange factor C9orf72

1

2

High-throughput

0.479

High

1404848

RING2
E3 ubiquitin-protein ligase RING2

1

1

High-throughput

0.479

High

1405711

NECD
Necdin

1

3

High-throughput

0.479

High

1412724

ESYT1
Extended synaptotagmin-1

1

1

High-throughput

0.479

High

1417529

FACD2
Fanconi anemia group D2 protein

1

4

High-throughput

0.479

High

1418533

ACE2
Angiotensin-converting enzyme 2

1

2

High-throughput

0.479

High

1419335

TRI55
Tripartite motif-containing protein 55

1

6

High-throughput

0.479

High

1429401

SPRTN
DNA-dependent metalloprotease SPRTN

1

3

High-throughput

0.479

High

1429891

TOLIP
Toll-interacting protein

1

1

High-throughput

0.479

High

1435471

EGLN3
Prolyl hydroxylase EGLN3

1

2

High-throughput

0.479

High

1436567

ECT2
Protein ECT2

1

6

High-throughput

0.479

High

1448855

TMPS4
Transmembrane protease serine 4

1

10

High-throughput

0.479

High

1459354

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.479

High

1460982

FBXL4
F-box/LRR-repeat protein 4

1

7

Small-scale

0.479

High

1461856

CLC4E
C-type lectin domain family 4 member E

1

5

High-throughput

0.479

High

1462363

FAF1
FAS-associated factor 1

1

7

High-throughput

0.479

High

1490550

GSTK1
Glutathione S-transferase kappa 1

1

1

High-throughput

0.479

High

1490552

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

4

Small-scale

0.479

High

1279105

RIC3
Protein RIC-3

1

0

High-throughput

0.458

High

339902

KLF8
Krueppel-like factor 8

1

6

High-throughput

0.457

High

1164

SIM26
Small integral membrane protein 26

1

2

High-throughput

0.445

High

256198

S19A2
Thiamine transporter 1

1

2

High-throughput

0.445

High

351264

MOT3
Monocarboxylate transporter 3

1

7

High-throughput

0.445

High

530612

TAU
Microtubule-associated protein tau

1

12

High-throughput

0.445

High

653661

HEMH
Ferrochelatase, mitochondrial

1

1

High-throughput

0.445

High

841282

CNDD3
Condensin-2 complex subunit D3

1

2

High-throughput

0.445

High

844109

HD
Huntingtin

1

5

High-throughput

0.445

High

1063028

DDR1
Epithelial discoidin domain-containing receptor 1

1

8

Small-scale

0.445

High

1130532

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

3

High-throughput

0.445

High

1131649

MFS10
Major facilitator superfamily domain-containing protein 10

1

7

High-throughput

0.445

High

1147712

TOM20
Mitochondrial import receptor subunit TOM20 homolog

1

5

High-throughput

0.445

High

1209808

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

4

High-throughput

0.445

High

1236381

MFSD5
Molybdate-anion transporter

1

2

High-throughput

0.445

High

1280829

S35E3
Solute carrier family 35 member E3

1

2

High-throughput

0.445

High

1329626

CD177
CD177 antigen

1

2

Small-scale

0.445

High

1348090

S35B2
Adenosine 3'-phospho 5'-phosphosulfate transporter 1

1

10

High-throughput

0.445

High

1407402

S29A1
Equilibrative nucleoside transporter 1

1

3

High-throughput

0.445

High

1417173

S12A9
Solute carrier family 12 member 9

1

3

High-throughput

0.445

High

122658

UBXN8
UBX domain-containing protein 8

1

7

High-throughput

0.437

High

164478

NRP1
Neuropilin-1

1

2

High-throughput

0.437

High

272561

OBSL1
Obscurin-like protein 1

1

3

High-throughput

0.437

High

332724

LYPD3
Ly6/PLAUR domain-containing protein 3

1

1

High-throughput

0.437

High

353634

AGR2
Anterior gradient protein 2 homolog

1

3

High-throughput

0.437

High

378884

CD4
T-cell surface glycoprotein CD4

1

2

Small-scale

0.437

High

769549

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.437

High

1031605

IFM3
Interferon-induced transmembrane protein 3

1

4

High-throughput

0.437

High

1126214

GRM2
Metabotropic glutamate receptor 2

1

2

High-throughput

0.437

High

1201914

PKHG4
Puratrophin-1

1

4

High-throughput

0.437

High

1218703

OTU1
Ubiquitin thioesterase OTU1

1

2

High-throughput

0.437

High

1249340

LMBRL
Protein LMBR1L

1

2

High-throughput

0.437

High

1253018

BAKOR
Beclin 1-associated autophagy-related key regulator

1

1

High-throughput

0.437

High

1256148

TRI67
Tripartite motif-containing protein 67

1

5

High-throughput

0.437

High

1288611

ZN598
E3 ubiquitin-protein ligase ZNF598

1

3

High-throughput

0.437

High

1327281

FBXL6
F-box/LRR-repeat protein 6

1

7

High-throughput

0.437

High

1329017

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

3

High-throughput

0.437

High

1360962

CLC4D
C-type lectin domain family 4 member D

1

5

High-throughput

0.437

High

1393836

DDRGK
DDRGK domain-containing protein 1

1

3

High-throughput

0.437

High

1415397

DUS23
Dual specificity protein phosphatase 23

1

3

High-throughput

0.437

High

1429775

ILKAP
Integrin-linked kinase-associated serine/threonine phosphatase 2C

1

2

High-throughput

0.437

High

1434263

PKHA4
Pleckstrin homology domain-containing family A member 4

1

6

High-throughput

0.437

High

1447460

ANLN
Anillin

1

3

High-throughput

0.437

High

1448333

FBX6
F-box only protein 6

1

1

High-throughput

0.437

High

1490551

AAR2
Protein AAR2 homolog

1

2

High-throughput

0.437

High

1326156

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.426

High

159

A0A024R6X4
PLEKHG4

1

4

High-throughput

0.407

High

255309

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

2

High-throughput

0.407

High

1007465

S35B1
Solute carrier family 35 member B1

1

8

High-throughput

0.407

High

1179043

S35G1
Solute carrier family 35 member G1

1

5

High-throughput

0.407

High

1246119

GTR7
Solute carrier family 2, facilitated glucose transporter member 7

1

4

High-throughput

0.407

High

1288950

RIMS1
Regulating synaptic membrane exocytosis protein 1

1

4

High-throughput

0.407

High

1335786

MOT11
Monocarboxylate transporter 11

1

7

High-throughput

0.407

High

1365141

SL9A6
Sodium/hydrogen exchanger 6

1

4

High-throughput

0.407

High

1391474

S35A4
Probable UDP-sugar transporter protein SLC35A4

1

3

High-throughput

0.407

High

1400198

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

2

High-throughput

0.407

High

1490548

S35A3
UDP-N-acetylglucosamine transporter

1

3

High-throughput

0.407

High

1490549

S27A5
Long-chain fatty acid transport protein 5

1

1

High-throughput

0.407

High

1458737

FA8A1
Protein FAM8A1

2

0

High-throughput

0.328

High

1243108

ERIC5
Glutamate-rich protein 5

1

0

High-throughput

0.279

Low

1336333

LS14A
Protein LSM14 homolog A

1

0

High-throughput

0.279

Low

1258730

ZN365
Protein ZNF365

1

0

High-throughput

0.269

Low

1178471

CL16A
Protein CLEC16A

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025