HitPredict

Interactor 1: TAF5L (O75529)
TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (TAF5L) (PCAF-associated factor 65 beta) (PAF65-beta)
Gene: TAF5L

Interactor 2: MAX (P61244)
Protein max (Class D basic helix-loop-helix protein 4) (bHLHd4) (Myc-associated factor X)
Gene: MAX

Species: Homo sapiens

Source: dip

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	12660246
Identification Methods	coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 589 Hs			1 160
+	Hs
		346159 LIS1_HUMAN (79-498): 2e-82: 265: 14.09		MYC_HUMAN (14-105): 1.81e-21: 91.5: 34.74
+	Mm
		1112323 FBXW7_MOUSE (299-588): 2.04e-69: 239: 23.02		SRBP2_MOUSE (19-149): 2.21e-30: 117: 26.32
+	Hs
		898168 FBXW7_HUMAN (299-588): 2.98e-69: 239: 23.02		MAX_HUMAN (1-160): 2.05e-31: 112: 100.00
+	Mm
		1257396 FBXW7_MOUSE (299-588): 2.04e-69: 239: 23.02		SRBP1_MOUSE (9-134): 2.94e-25: 102: 19.38
+	Hs
		738987 FBXW7_HUMAN (299-588): 2.98e-69: 239: 23.02		SRBP1_HUMAN (9-149): 2.92e-25: 102: 20.00
+	Mm
		348444 FBXW7_MOUSE (299-588): 2.04e-69: 239: 23.02		MYC_MOUSE (19-105): 1.04e-21: 91.9: 37.50
+	Hs
		347517 FBXW7_HUMAN (299-588): 2.98e-69: 239: 23.02		MYC_HUMAN (14-105): 1.81e-21: 91.5: 34.74
+	Hs
		379688 FBXW7_HUMAN (299-588): 2.98e-69: 239: 23.02		MYCN_HUMAN (7-101): 2.1e-21: 91.1: 33.67
+	Hs
		267737 TAF5L_HUMAN (346-587): 2.5e-63: 220: 24.09		MYOD1_HUMAN (11-151): 1.24e-24: 98.4: 16.33
+	Hs
		267729 TAF5L_HUMAN (346-587): 2.5e-63: 220: 24.09		MYC_HUMAN (14-105): 1.81e-21: 91.5: 34.74
+	Hs
		267736 TAF5L_HUMAN (346-587): 2.5e-63: 220: 24.09		MYCL_HUMAN (7-104): 3.77e-20: 86.9: 30.77
+	Hs
		348035 NLE1_HUMAN (417-588): 2.76e-49: 179: 30.34		MYC_HUMAN (14-105): 1.81e-21: 91.5: 34.74
+	Hs
		245557 TBL1X_HUMAN (148-415): 5.11e-40: 155: 14.24		MYOD1_HUMAN (11-151): 1.24e-24: 98.4: 16.33
+	Mm
		659344 WDR5_MOUSE (498-588): 8.41e-16: 80.9: 20.88		MAX_MOUSE (1-160): 4.6e-32: 113: 99.38
+	Hs
		898091 WDR5_HUMAN (498-588): 8.41e-16: 80.9: 20.88		MAX_HUMAN (1-160): 2.05e-31: 112: 100.00
+	Hs
		607803 WDR5_HUMAN (498-588): 8.41e-16: 80.9: 20.88		USF1_HUMAN (10-115): 4.62e-23: 94.1: 30.97
+	Hs
		346404 WDR5_HUMAN (498-588): 8.41e-16: 80.9: 20.88		MYC_HUMAN (14-105): 1.81e-21: 91.5: 34.74
+	Hs
		379200 WDR5_HUMAN (498-588): 8.41e-16: 80.9: 20.88		MYCN_HUMAN (7-101): 2.1e-21: 91.1: 33.67
+	Hs
		347550 SNR40_HUMAN (162-294): 1.95e-10: 64.7: 7.86		MYC_HUMAN (14-105): 1.81e-21: 91.5: 34.74
+	Hs
		379701 SNR40_HUMAN (162-294): 1.95e-10: 64.7: 7.86		MYCN_HUMAN (7-101): 2.1e-21: 91.1: 33.67