HitPredict

Interactor 1: EED (O75530)
Polycomb protein EED (hEED) (Embryonic ectoderm development protein) (WD protein associating with integrin cytoplasmic tails 1) (WAIT-1)
Gene: EED

Interactor 2: FLNA (P21333)
Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin)
Gene: FLNA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37689310
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 441 Hs			1 2647
+	Mm
		1207253 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		FLNA_MOUSE (1-2647): 0: 2784: 97.32
+	Mm
		1194440 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		FLNB_MOUSE (28-2647): 0: 2675: 68.91
+	Hs
		598240 POC1B_HUMAN (186-440): 4.25e-48: 173: 15.56		FLNA_HUMAN (1-2647): 0: 2776: 100.00
+	Hs
		598260 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		FLNA_HUMAN (1-2647): 0: 2776: 100.00
+	Hs
		598268 SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29		FLNA_HUMAN (1-2647): 0: 2776: 100.00
+	Hs
		598209 WDR5B_HUMAN (279-439): 2.9e-21: 96.1: 12.27		FLNA_HUMAN (1-2647): 0: 2776: 100.00
+	Hs
		598345 NLE1_HUMAN (4-124): 2.95e-18: 88.8: 9.09		FLNA_HUMAN (1-2647): 0: 2776: 100.00
+	Hs
		598398 WSB1_HUMAN (162-437): 7.57e-17: 84: 21.35		FLNA_HUMAN (1-2647): 0: 2776: 100.00
+	Hs
		597996 LIS1_HUMAN (332-438): 2.37e-14: 76.5: 18.69		FLNA_HUMAN (1-2647): 0: 2776: 100.00
+	Hs
		598040 WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09		FLNA_HUMAN (1-2647): 0: 2776: 100.00
+	Hs
		598367 FBW1B_HUMAN (160-352): 1.57e-12: 71.3: 18.97		FLNA_HUMAN (1-2647): 0: 2776: 100.00
+	Hs
		261236 WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09		FLNB_HUMAN (28-2647): 0: 2710: 69.63
+	Hs
		1052959 FBW1B_HUMAN (160-352): 1.57e-12: 71.3: 18.97		FLNC_HUMAN (32-2647): 0: 1432: 35.96
+	Mm
		1143724 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		SPTB2_MOUSE (22-460): 2.2e-118: 423: 24.62
+	Mm
		1186639 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		ACTN1_MOUSE (20-459): 2.62e-118: 400: 24.12
+	Mm
		885090 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		ACTN4_MOUSE (23-382): 3.46e-112: 383: 26.47
+	Hs
		903137 WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09		SPTB2_HUMAN (22-460): 2.2e-118: 423: 24.62
+	Mm
		984806 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		PGBM_MOUSE (323-1247): 1.86e-28: 128: 11.93
+	Hs
		957555 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		PGBM_HUMAN (181-1251): 3.53e-32: 140: 12.81
+	Hs
		957556 SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29		PGBM_HUMAN (181-1251): 3.53e-32: 140: 12.81