Protein: EXOC4
Exocyst complex component 4 (Exocyst complex component Sec8)

Gene: EXOC4
Organism: Homo sapiens
Interactions: 207
UniProt ID: Q96A65

Gene Ontology (top 5):
GO:0000145 - exocyst
GO:0000281 - mitotic cytokinesis
GO:0005737 - cytoplasm
GO:0005813 - centrosome
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1382593

EXOC1
Exocyst complex component 1

8

0

Small-scale

0.918

High

1382568

EXOC2
Exocyst complex component 2

4

2

Small-scale

0.895

High

137259

EXOC5
Exocyst complex component 5

2

2

Small-scale

0.789

High

252894

EXOC3
Exocyst complex component 3

9

7

Small-scale

0.751

High

1315112

EXOC8
Exocyst complex component 8

4

2

Small-scale

0.704

High

1347236

EXOC6
Exocyst complex component 6

4

2

Small-scale

0.697

High

1382607

EXOC7
Exocyst complex component 7

4

3

Small-scale

0.696

High

343433

SNP29
Synaptosomal-associated protein 29

4

0

High-throughput

0.670

High

1382565

DTBP1
Dysbindin

4

0

High-throughput

0.669

High

482947

TPM1
Tropomyosin alpha-1 chain

3

1

High-throughput

0.667

High

774542

BASI
Basigin

3

0

High-throughput

0.638

High

1139788

SETB1
Histone-lysine N-methyltransferase SETDB1

3

0

High-throughput

0.638

High

286700

STX11
Syntaxin-11

2

2

High-throughput

0.628

High

771196

APJ
Apelin receptor

2

3

High-throughput

0.628

High

1140126

IQCB1
IQ calmodulin-binding motif-containing protein 1

2

1

High-throughput

0.628

High

1382584

RABE2
Rab GTPase-binding effector protein 2

2

1

High-throughput

0.628

High

1382610

EXC6B
Exocyst complex component 6B

2

2

High-throughput

0.628

High

1006088

DLG4
Disks large homolog 4

2

3

Small-scale

0.624

High

564174

CFTR
Cystic fibrosis transmembrane conductance regulator

2

0

High-throughput

0.602

High

699568

IL1R2
Interleukin-1 receptor type 2

2

0

High-throughput

0.602

High

1382602

GGA1
ADP-ribosylation factor-binding protein GGA1

2

0

High-throughput

0.602

High

363684

EGFR
Epidermal growth factor receptor

2

1

Small-scale

0.594

High

1382571

SCLT1
Sodium channel and clathrin linker 1

2

1

High-throughput

0.588

High

242521

PRKN
E3 ubiquitin-protein ligase parkin

2

1

High-throughput

0.584

High

1227209

A16L1
Autophagy-related protein 16-1

2

2

High-throughput

0.584

High

352216

MBD3
Methyl-CpG-binding domain protein 3

2

0

High-throughput

0.580

High

1350680

CCHCR
Coiled-coil alpha-helical rod protein 1

2

0

High-throughput

0.580

High

1368924

GOGA1
Golgin subfamily A member 1

2

0

High-throughput

0.580

High

1368710

DLG3
Disks large homolog 3

1

3

Small-scale

0.573

High

1327776

SH2D3
SH2 domain-containing protein 3C

2

1

High-throughput

0.571

High

976472

RB11A
Ras-related protein Rab-11A

2

0

High-throughput

0.559

High

1382570

CEP63
Centrosomal protein of 63 kDa

2

0

High-throughput

0.551

High

1382590

DISC1
Disrupted in schizophrenia 1 protein

2

0

High-throughput

0.551

High

923621

TTC3
E3 ubiquitin-protein ligase TTC3

1

1

High-throughput

0.541

High

182713

GP182
G-protein coupled receptor 182

1

5

High-throughput

0.536

High

227256

KRT86
Keratin, type II cuticular Hb6

1

2

High-throughput

0.536

High

300811

KRT38
Keratin, type I cuticular Ha8

1

4

High-throughput

0.536

High

447827

TPM3
Tropomyosin alpha-3 chain

1

1

High-throughput

0.536

High

956968

CXCR4
C-X-C chemokine receptor type 4

1

3

High-throughput

0.536

High

967227

RRAS2
Ras-related protein R-Ras2

1

3

High-throughput

0.536

High

1007499

KRT83
Keratin, type II cuticular Hb3

1

2

High-throughput

0.536

High

1101617

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

3

High-throughput

0.536

High

1127821

KRT81
Keratin, type II cuticular Hb1

1

2

High-throughput

0.536

High

1142132

P2RY6
P2Y purinoceptor 6

1

4

High-throughput

0.536

High

1144856

RABE1
Rab GTPase-binding effector protein 1

1

1

High-throughput

0.536

High

1277597

K1C27
Keratin, type I cytoskeletal 27

1

4

High-throughput

0.536

High

1290444

EX3L1
Exocyst complex component 3-like protein

1

7

High-throughput

0.536

High

1349426

POC1B
POC1 centriolar protein homolog B

1

1

High-throughput

0.536

High

1363781

YLAT2
Y+L amino acid transporter 2

1

1

High-throughput

0.536

High

1382573

CML1
Chemerin-like receptor 1

1

4

High-throughput

0.536

High

1382600

VPS51
Vacuolar protein sorting-associated protein 51 homolog

1

3

High-throughput

0.536

High

1382589

BIRC6
Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6

1

1

Small-scale

0.515

High

317661

ATG12
Ubiquitin-like protein ATG12

1

0

Small-scale

0.513

High

827238

ARL1
ADP-ribosylation factor-like protein 1

1

0

High-throughput

0.513

High

867329

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.513

High

1258662

IKIP
Inhibitor of nuclear factor kappa-B kinase-interacting protein

1

0

High-throughput

0.513

High

1291649

CMTD1
Catechol O-methyltransferase domain-containing protein 1

1

0

High-throughput

0.513

High

1382572

CDC5L
Cell division cycle 5-like protein

1

0

High-throughput

0.513

High

1382576

SIKE1
Suppressor of IKBKE 1

1

0

High-throughput

0.513

High

1382577

HAUS8
HAUS augmin-like complex subunit 8

1

0

High-throughput

0.513

High

1382578

SPZ1
Spermatogenic leucine zipper protein 1

1

0

High-throughput

0.513

High

1382582

ATG5
Autophagy protein 5

1

0

Small-scale

0.513

High

243992

JIP4
C-Jun-amino-terminal kinase-interacting protein 4

1

0

Small-scale

0.493

High

831196

CCNF
Cyclin-F

1

0

High-throughput

0.493

High

1126736

BECN1
Beclin-1

1

0

Small-scale

0.493

High

1290521

LAP4B
Lysosomal-associated transmembrane protein 4B

1

0

Small-scale

0.493

High

1382599

CTNA3
Catenin alpha-3

1

0

High-throughput

0.493

High

1200054

EIPR1
EARP and GARP complex-interacting protein 1

1

1

High-throughput

0.489

High

1323278

KT222
Keratin-like protein KRT222

1

5

High-throughput

0.489

High

259027

DNJA2
DnaJ homolog subfamily A member 2

1

2

High-throughput

0.479

High

374117

RASN
GTPase NRas

1

4

High-throughput

0.479

High

375814

RASK
GTPase KRas

1

3

High-throughput

0.479

High

412401

NTRK1
High affinity nerve growth factor receptor

1

2

High-throughput

0.479

High

475653

K1C19
Keratin, type I cytoskeletal 19

1

4

High-throughput

0.479

High

539835

RALA
Ras-related protein Ral-A

1

5

Small-scale

0.479

High

539898

RALB
Ras-related protein Ral-B

1

5

High-throughput

0.479

High

541627

FGFR1
Fibroblast growth factor receptor 1

1

2

High-throughput

0.479

High

560474

IFM1
Interferon-induced transmembrane protein 1

1

1

High-throughput

0.479

High

570539

GFAP
Glial fibrillary acidic protein

1

4

High-throughput

0.479

High

626321

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

1

High-throughput

0.479

High

727914

DNJA1
DnaJ homolog subfamily A member 1

1

2

High-throughput

0.479

High

833333

PERI
Peripherin

1

4

High-throughput

0.479

High

883307

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

1

High-throughput

0.479

High

966714

1433G
14-3-3 protein gamma

1

2

High-throughput

0.479

High

1031485

IFM3
Interferon-induced transmembrane protein 3

1

1

High-throughput

0.479

High

1049645

1433F
14-3-3 protein eta

1

2

High-throughput

0.479

High

1091550

DLG1
Disks large homolog 1

1

3

Small-scale

0.479

High

1098530

NMDE2
Glutamate receptor ionotropic, NMDA 2B

1

4

Small-scale

0.479

High

1107665

MTM1
Myotubularin

1

1

Small-scale

0.479

High

1151492

IKBB
NF-kappa-B inhibitor beta

1

1

High-throughput

0.479

High

1178974

EX3L2
Exocyst complex component 3-like protein 2

1

7

Small-scale

0.479

High

1251936

LMTK1
Serine/threonine-protein kinase LMTK1

1

3

High-throughput

0.479

High

1286858

TM11B
Transmembrane protease serine 11B

1

1

High-throughput

0.479

High

1312208

MIRO2
Mitochondrial Rho GTPase 2

1

2

High-throughput

0.479

High

1380067

FBXW7
F-box/WD repeat-containing protein 7

1

1

High-throughput

0.479

High

1382567

DDRGK
DDRGK domain-containing protein 1

1

1

High-throughput

0.479

High

1382569

SNX27
Sorting nexin-27

1

1

High-throughput

0.479

High

1382591

TMPS4
Transmembrane protease serine 4

1

1

High-throughput

0.479

High

1382595

MTMR4
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR4

1

1

High-throughput

0.479

High

1382601

ANC2
Anaphase-promoting complex subunit 2

1

1

High-throughput

0.479

High

1382606

ALK
ALK tyrosine kinase receptor

1

2

High-throughput

0.479

High

1382612

MYO5A
Unconventional myosin-Va

1

1

Small-scale

0.479

High

69398

WASH1
WASH complex subunit 1

1

0

Small-scale

0.458

High

164038

NDC80
Kinetochore protein NDC80 homolog

1

0

High-throughput

0.458

High

189762

STX7
Syntaxin-7

1

0

High-throughput

0.458

High

226163

STX6
Syntaxin-6

1

0

High-throughput

0.458

High

276790

TBCA
Tubulin-specific chaperone A

1

0

High-throughput

0.458

High

278929

PEX14
Peroxisomal membrane protein PEX14

1

0

High-throughput

0.458

High

290099

OFD1
Centriole and centriolar satellite protein OFD1

1

0

High-throughput

0.458

High

322438

HAUS5
HAUS augmin-like complex subunit 5

1

0

High-throughput

0.458

High

342006

CEP43
Centrosomal protein 43

1

0

High-throughput

0.458

High

346166

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

390714

TFR1
Transferrin receptor protein 1

1

0

High-throughput

0.458

High

440168

LCK
Tyrosine-protein kinase Lck

1

0

High-throughput

0.458

High

530185

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.458

High

551189

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.458

High

552664

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

0

High-throughput

0.458

High

580672

AMPN
Aminopeptidase N

1

0

High-throughput

0.458

High

604145

CXA1
Gap junction alpha-1 protein

1

0

High-throughput

0.458

High

643012

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

0

High-throughput

0.458

High

693050

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.458

High

708997

T2EB
Transcription initiation factor IIE subunit beta

1

0

High-throughput

0.458

High

710415

EPHA2
Ephrin type-A receptor 2

1

0

High-throughput

0.458

High

721048

CLIP1
CAP-Gly domain-containing linker protein 1

1

0

High-throughput

0.458

High

731524

STIP1
Stress-induced-phosphoprotein 1

1

0

High-throughput

0.458

High

904052

BAP31
B-cell receptor-associated protein 31

1

0

High-throughput

0.458

High

980104

H4
Histone H4

1

0

High-throughput

0.458

High

991899

DYLT1
Dynein light chain Tctex-type 1

1

0

High-throughput

0.458

High

1004939

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.458

High

1026496

HSF1
Heat shock factor protein 1

1

0

High-throughput

0.458

High

1041221

CAV1
Caveolin-1

1

0

High-throughput

0.458

High

1088950

TP53B
TP53-binding protein 1

1

0

Small-scale

0.458

High

1108007

SQSTM
Sequestosome-1

1

0

High-throughput

0.458

High

1109970

HDAC1
Histone deacetylase 1

1

0

High-throughput

0.458

High

1110673

DCTN2
Dynactin subunit 2

1

0

High-throughput

0.458

High

1114988

CUL4A
Cullin-4A

1

0

High-throughput

0.458

High

1143459

PCM1
Pericentriolar material 1 protein

1

0

High-throughput

0.458

High

1156567

CCDC6
Coiled-coil domain-containing protein 6

1

0

High-throughput

0.458

High

1203217

ODFP2
Outer dense fiber protein 2

1

0

High-throughput

0.458

High

1214542

ACBD5
Acyl-CoA-binding domain-containing protein 5

1

0

High-throughput

0.458

High

1228557

HAUS3
HAUS augmin-like complex subunit 3

1

0

High-throughput

0.458

High

1229030

RNF43
E3 ubiquitin-protein ligase RNF43

1

0

High-throughput

0.458

High

1233403

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.458

High

1246915

RICTR
Rapamycin-insensitive companion of mTOR

1

0

High-throughput

0.458

High

1249088

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

1254957

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1256546

CE128
Centrosomal protein of 128 kDa

1

0

High-throughput

0.458

High

1278421

HAUS6
HAUS augmin-like complex subunit 6

1

0

High-throughput

0.458

High

1280896

CNTRL
Centriolin

1

0

High-throughput

0.458

High

1322769

CNTRB
Centrobin

1

0

High-throughput

0.458

High

1326292

NIN
Ninein

1

0

High-throughput

0.458

High

1366504

AKAP1
A-kinase anchor protein 1, mitochondrial

1

0

High-throughput

0.458

High

1382562

CLUA1
Clusterin-associated protein 1

1

0

High-throughput

0.458

High

1382564

HAUS1
HAUS augmin-like complex subunit 1

1

0

High-throughput

0.458

High

1382574

HAUS7
HAUS augmin-like complex subunit 7

1

0

High-throughput

0.458

High

1382579

CEP44
Centrosomal protein of 44 kDa

1

0

High-throughput

0.458

High

1382580

WWTR1
WW domain-containing transcription regulator protein 1

1

0

High-throughput

0.458

High

1382583

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

1382585

HAUS4
HAUS augmin-like complex subunit 4

1

0

High-throughput

0.458

High

1382586

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1382587

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.458

High

1382588

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

0

High-throughput

0.458

High

1382596

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

1382597

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1382598

TBK1
Serine/threonine-protein kinase TBK1

1

0

Small-scale

0.458

High

1382609

MARE3
Microtubule-associated protein RP/EB family member 3

1

0

High-throughput

0.458

High

166381

ZNT4
Probable proton-coupled zinc antiporter SLC30A4

1

1

High-throughput

0.445

High

638488

FPR1
fMet-Leu-Phe receptor

1

4

High-throughput

0.445

High

1310911

ZNT8
Proton-coupled zinc antiporter SLC30A8

1

1

High-throughput

0.445

High

1382608

XCT
Cystine/glutamate transporter

1

1

High-throughput

0.445

High

630923

RAB4A
Ras-related protein Rab-4A

1

1

High-throughput

0.437

High

171548

S27A2
Long-chain fatty acid transport protein 2

1

0

High-throughput

0.426

High

262281

SCN2B
Sodium channel regulatory subunit beta-2

1

0

High-throughput

0.426

High

388268

GLPA
Glycophorin-A

1

0

High-throughput

0.426

High

516774

SCHI1
Schwannomin-interacting protein 1

1

0

High-throughput

0.426

High

1382592

S39A9
Zinc transporter ZIP9

1

0

High-throughput

0.426

High

1382611

NOC2L
Nucleolar complex protein 2 homolog

1

0

High-throughput

0.426

High

1379984

SMCE1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

2

0

High-throughput

0.316

High

1382603

ING1
Inhibitor of growth protein 1

2

0

High-throughput

0.316

High

372779

MYC
Myc proto-oncogene protein

2

0

High-throughput

0.313

High

1382575

KXDL1
KxDL motif-containing protein 1

2

0

High-throughput

0.313

High

1382605

HECD1
E3 ubiquitin-protein ligase HECTD1

2

0

Small-scale

0.305

High

50922

SYCE3
Synaptonemal complex central element protein 3

1

0

High-throughput

0.279

Low

1111169

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.279

Low

1179829

INSY1
Inhibitory synaptic factor 1

1

0

High-throughput

0.279

Low

1382581

UN93B
Protein unc-93 homolog B1

1

0

High-throughput

0.279

Low

106418

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

139956

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

0

High-throughput

0.249

Low

246839

KDM1A
Lysine-specific histone demethylase 1A

1

0

High-throughput

0.249

Low

298770

ATP5H
ATP synthase peripheral stalk subunit d, mitochondrial

1

0

High-throughput

0.249

Low

352511

TOP3B
DNA topoisomerase 3-beta-1

1

0

High-throughput

0.249

Low

419128

H2A1B
Histone H2A type 1-B/E

1

0

High-throughput

0.249

Low

589351

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

696147

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

768836

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

1100204

TIF1B
Transcription intermediary factor 1-beta

1

0

High-throughput

0.249

Low

1194536

HYDIN
Hydrocephalus-inducing protein homolog

1

0

High-throughput

0.249

Low

1276603

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

1293106

TMM17
Transmembrane protein 17

1

0

High-throughput

0.249

Low

1366969

ESR2
Estrogen receptor beta

1

0

High-throughput

0.249

Low

1382563

PF21A
PHD finger protein 21A

1

0

High-throughput

0.249

Low

1382566

BORC6
BLOC-1-related complex subunit 6

1

0

High-throughput

0.249

Low

1382604

RCOR1
REST corepressor 1

1

0

High-throughput

0.249

Low

1096

SIM26
Small integral membrane protein 26

1

0

High-throughput

0.232

Low

430211

JUN
Transcription factor Jun

1

0

High-throughput

0.232

Low

1167095

WHAL1
Putative WASP homolog-associated protein with actin, membranes and microtubules-like protein 1

1

0

High-throughput

0.232

Low

1382594

MED29
Mediator of RNA polymerase II transcription subunit 29

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025