HitPredict

Interactor 1: EED (O75530)
Polycomb protein EED (hEED) (Embryonic ectoderm development protein) (WD protein associating with integrin cytoplasmic tails 1) (WAIT-1)
Gene: EED

Interactor 2: PP1R8 (Q12972)
Nuclear inhibitor of protein phosphatase 1 (NIPP-1) (Protein phosphatase 1 regulatory inhibitor subunit 8) [Includes: Activator of RNA decay (EC 3.1.4.-) (ARD-1)]
Gene: PPP1R8

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.67	0.60	0.636

Property	Details
Experiments	12788942, 17804093
Identification Methods	affinity chromatography technology, two hybrid, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 441 Hs			1 351
+	Hs
		1021775 SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29		PP1R8_HUMAN (1-351): 4.3e-169: 476: 100.00
+	Mm
		1206705 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		SNIP1_MOUSE (14-135): 5.19e-39: 144: 28.57
+	Mm
		1193512 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		C170B_MOUSE (39-179): 9.49e-34: 134: 18.44
+	Hs
		1288285 SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29		NADAP_HUMAN (3-222): 6.13e-63: 215: 23.73
+	Hs
		1131796 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		CE170_HUMAN (38-195): 1.36e-33: 133: 17.07
+	Hs
		1281511 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		C170B_HUMAN (39-179): 5.02e-33: 131: 20.57
+	Hs
		1250982 SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29		SNIP1_HUMAN (14-135): 9.77e-39: 143: 28.57
+	Hs
		1231913 SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29		AGGF1_HUMAN (50-221): 9.97e-29: 119: 18.42
+	Hs
		197057 PRP4_HUMAN (337-437): 3.12e-09: 60.7: 16.51		SNIP1_HUMAN (14-135): 9.77e-39: 143: 28.57