HitPredict

Interactor 1: EED (O75530)
Polycomb protein EED (hEED) (Embryonic ectoderm development protein) (WD protein associating with integrin cytoplasmic tails 1) (WAIT-1)
Gene: EED

Interactor 2: ABCF1 (Q8NE71)
ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50) (TNF-alpha-stimulated ABC protein)
Gene: ABCF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	24457600, 26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 441 Hs			1 845
+	Mm
		1159855 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		ABCF1_MOUSE (1-845): 1.01e-145: 452: 88.77
+	Hs
		1242914 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		ABCF1_HUMAN (1-845): 1.12e-157: 483: 100.00
+	Hs
		903373 WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09		ABCF1_HUMAN (1-845): 1.12e-157: 483: 100.00
+	Mm
		1225144 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		ABCF3_MOUSE (609-845): 8.89e-31: 131: 18.84
+	Mm
		1265423 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		ABCF2_MOUSE (636-843): 5.96e-26: 115: 18.80
+	Hs
		1281453 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		ABCF2_HUMAN (636-843): 3.58e-26: 116: 18.38