HitPredict

Interactor 1: EED (O75530)
Polycomb protein EED (hEED) (Embryonic ectoderm development protein) (WD protein associating with integrin cytoplasmic tails 1) (WAIT-1)
Gene: EED

Interactor 2: DCA13 (Q9NV06)
DDB1- and CUL4-associated factor 13 (WD repeat and SOF domain-containing protein 1)
Gene: DCAF13

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24457600
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	eIF2A~WD40, Sof1~WD40, WD40~WD40
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 441 Hs			1 445
+	Mm
		1160681 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		DCA13_MOUSE (1-445): 2.93e-113: 341: 89.04
+	Mm
		1208593 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		COPA_MOUSE (36-341): 1.23e-45: 171: 16.67
+	Hs
		268333 EED_HUMAN (1-441): 2.11e-92: 287: 100.00		PRP19_HUMAN (169-372): 1.15e-22: 102: 13.53
+	Hs
		245630 TBL1X_HUMAN (13-441): 1.12e-73: 243: 11.39		TBL1Y_HUMAN (236-445): 4.15e-37: 144: 11.56
+	Mm
		1265418 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		PRP19_MOUSE (169-372): 6.69e-22: 99.8: 13.04
+	Hs
		268049 EED_HUMAN (1-441): 2.11e-92: 287: 100.00		TBL3_HUMAN (289-436): 7.69e-11: 66.3: 5.13
+	Hs
		245633 TBL1X_HUMAN (13-441): 1.12e-73: 243: 11.39		TBL1R_HUMAN (267-445): 1.46e-25: 110: 10.59
+	Hs
		1309163 TBL1R_HUMAN (4-335): 2.6e-56: 195: 11.40		TBL1Y_HUMAN (236-445): 4.15e-37: 144: 11.56
+	Hs
		245546 TBL1X_HUMAN (13-441): 1.12e-73: 243: 11.39		TBL1X_HUMAN (315-435): 1.86e-17: 86.7: 10.95
+	Hs
		863508 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		COPA_HUMAN (36-341): 1.01e-45: 171: 16.67
+	Hs
		1240442 POC1A_HUMAN (177-440): 1.72e-50: 177: 14.29		POC1B_HUMAN (313-439): 1.21e-23: 104: 7.75
+	Sc
		630844 NLE1_YEAST (4-263): 1.23e-51: 183: 14.05		NLE1_YEAST (308-440): 4.25e-21: 97.5: 8.33
+	Hs
		903418 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		WDR5_HUMAN (311-444): 1.54e-27: 114: 9.49
+	Dm
		1358859 FBXW7_DROME (224-441): 2.22e-25: 111: 15.53		WDS_DROME (311-444): 2.19e-27: 114: 9.49
+	Hs
		1281473 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		PRP19_HUMAN (169-372): 1.15e-22: 102: 13.53
+	Dm
		1358845 WDS_DROME (267-440): 1.02e-23: 103: 15.34		WDS_DROME (311-444): 2.19e-27: 114: 9.49
+	Hs
		903428 SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29		WDR5_HUMAN (311-444): 1.54e-27: 114: 9.49
+	Hs
		1016312 SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29		TBL3_HUMAN (289-436): 7.69e-11: 66.3: 5.13