HitPredict

Interactor 1: EED (O75530)
Polycomb protein EED (hEED) (Embryonic ectoderm development protein) (WD protein associating with integrin cytoplasmic tails 1) (WAIT-1)
Gene: EED

Interactor 2: TRRAP (Q9Y4A5)
Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog)
Gene: TRRAP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	24457600, 35906200
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PI3_PI4_kinase~WD40
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 441 Hs			1 3859
+	Mm
		93819 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		E9QLK7_MOUSE (1-3859): 0: 4359: 97.35
+	Hs
		1074814 TAF5_HUMAN (173-441): 4.8e-16: 82.5: 21.19		TRRAP_HUMAN (1-3859): 0: 4445: 100.00
+	Hs
		903639 WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09		TRRAP_HUMAN (1-3859): 0: 4445: 100.00
+	Mm
		956216 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		PRKDC_MOUSE (1935-3859): 0: 1042: 13.78
+	Hs
		268021 EED_HUMAN (1-441): 2.11e-92: 287: 100.00		PRKDC_HUMAN (1935-3859): 0: 960: 12.88
+	Hs
		787538 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		MTOR_HUMAN (2163-3858): 0: 984: 14.90
+	Mm
		1257393 FBXW7_MOUSE (219-439): 5.6e-28: 118: 15.32		MTOR_MOUSE (2163-3858): 0: 980: 14.80
+	Hs
		944360 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		PRKDC_HUMAN (1935-3859): 0: 960: 12.88
+	Hs
		787437 WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09		MTOR_HUMAN (2163-3858): 0: 984: 14.90
+	Hs
		903121 WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09		PRKDC_HUMAN (1935-3859): 0: 960: 12.88