HitPredict

Interactor 1: WBP4 (O75554)
WW domain-binding protein 4 (WBP-4) (Formin-binding protein 21) (WW domain-containing-binding protein 4)
Gene: WBP4

Interactor 2: SNRPA (P09012)
U1 small nuclear ribonucleoprotein A (U1 snRNP A) (U1-A) (U1A)
Gene: SNRPA

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.605

Property	Details
Experiments	34133714, 16055720
Identification Methods	two hybrid, pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 376 Hs			1 282
+	Hs
		269201 WBP4_HUMAN (1-376): 3.94e-99: 300: 100.00		PABP1_HUMAN (10-219): 3.06e-20: 92.2: 15.09
+	Hs
		263479 PR40A_HUMAN (98-260): 1.44e-31: 128: 21.47		SNRPA_HUMAN (1-282): 4.82e-60: 193: 100.00
+	Hs
		263477 PR40A_HUMAN (98-260): 1.44e-31: 128: 21.47		RU2B_HUMAN (5-282): 1.37e-59: 190: 46.40
+	Hs
		263528 PR40A_HUMAN (98-260): 1.44e-31: 128: 21.47		PTBP1_HUMAN (1-281): 2.58e-55: 189: 20.42
+	Sc
		696625 PRP40_YEAST (126-271): 6.69e-26: 110: 21.92		RU1A_YEAST (1-281): 3.81e-48: 163: 20.42
+	Hs
		125102 WWP2_HUMAN (21-243): 7.51e-12: 69: 13.90		RU2B_HUMAN (5-282): 1.37e-59: 190: 46.40
+	Hs
		125167 WWP2_HUMAN (21-243): 7.51e-12: 69: 13.90		PTBP1_HUMAN (1-281): 2.58e-55: 189: 20.42
+	Sc
		693971 PRP40_YEAST (126-271): 6.69e-26: 110: 21.92		PUB1_YEAST (11-282): 2.91e-39: 144: 18.25
+	Sc
		376704 PRP40_YEAST (126-271): 6.69e-26: 110: 21.92		PABP_YEAST (3-199): 1.47e-17: 84.2: 10.05
+	Hs
		125122 WWP2_HUMAN (21-243): 7.51e-12: 69: 13.90		PABP1_HUMAN (10-219): 3.06e-20: 92.2: 15.09
+	Hs
		125430 WWP2_HUMAN (21-243): 7.51e-12: 69: 13.90		PABP4_HUMAN (11-199): 1.25e-18: 87.6: 18.42