Protein: MBD1
Methyl-CpG-binding domain protein 1 (CXXC-type zinc finger protein 3) (Methyl-CpG-binding protein MBD1) (Protein containing methyl-CpG-binding domain 1)

Gene: MBD1
Organism: Homo sapiens
Interactions: 76
UniProt ID: Q9UIS9

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0003229 - ventricular cardiac muscle tissue development
GO:0003677 - DNA binding
GO:0003682 - chromatin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1065746

SETB1
Histone-lysine N-methyltransferase SETDB1

2

16

Small-scale

0.830

High

177400

HDAC3
Histone deacetylase 3

1

20

Small-scale

0.730

High

1024534

CAF1A
Chromatin assembly factor 1 subunit A

3

4

Small-scale

0.686

High

1167135

MCAF1
Activating transcription factor 7-interacting protein 1

3

7

Small-scale

0.672

High

800551

CBX5
Chromobox protein homolog 5

3

20

Small-scale

0.671

High

1038793

HDAC1
Histone deacetylase 1

1

20

Small-scale

0.665

High

1270510

HDAC2
Histone deacetylase 2

1

20

Small-scale

0.665

High

278185

PIAS1
E3 SUMO-protein ligase PIAS1

2

2

Small-scale

0.639

High

203807

SUV91
Histone-lysine N-methyltransferase SUV39H1

1

6

Small-scale

0.578

High

370660

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

123339

CBX4
E3 SUMO-protein ligase CBX4

1

20

Small-scale

0.561

High

1304167

RING2
E3 ubiquitin-protein ligase RING2

1

20

Small-scale

0.561

High

1237514

CGAS
Cyclic GMP-AMP synthase

2

0

Small-scale

0.559

High

792065

HD
Huntingtin

1

0

High-throughput

0.543

High

644197

EF1G
Elongation factor 1-gamma

1

1

High-throughput

0.541

High

804362

NOTC1
Neurogenic locus notch homolog protein 1

1

4

High-throughput

0.541

High

990380

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

1

High-throughput

0.541

High

1022466

TIAM1
Rho guanine nucleotide exchange factor TIAM1

1

1

High-throughput

0.541

High

1273671

DVL3
Segment polarity protein dishevelled homolog DVL-3

1

2

High-throughput

0.541

High

1355890

NOTC3
Neurogenic locus notch homolog protein 3

1

4

High-throughput

0.541

High

157091

AIM2
Interferon-inducible protein AIM2

1

4

High-throughput

0.536

High

309137

KI20A
Kinesin-like protein KIF20A

1

4

High-throughput

0.536

High

455979

PARP1
Poly [ADP-ribose] polymerase 1

1

10

High-throughput

0.536

High

987012

SUH
Recombining binding protein suppressor of hairless

1

5

High-throughput

0.536

High

1153966

IFIX
Pyrin and HIN domain-containing protein 1

1

4

High-throughput

0.536

High

1305487

KIF2C
Kinesin-like protein KIF2C

1

4

High-throughput

0.536

High

1303475

NELL2
Protein kinase C-binding protein NELL2

1

6

High-throughput

0.532

High

1355892

PIAS3
E3 SUMO-protein ligase PIAS3

1

2

Small-scale

0.529

High

278348

PIAS2
E3 SUMO-protein ligase PIAS2

1

2

Small-scale

0.527

High

149771

COPE
Coatomer subunit epsilon

1

0

High-throughput

0.518

High

1035658

SNPC2
snRNA-activating protein complex subunit 2

1

0

High-throughput

0.518

High

1257281

ZN384
Zinc finger protein 384

1

0

High-throughput

0.518

High

1306284

MDFI
MyoD family inhibitor

1

0

High-throughput

0.518

High

786444

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

2

Small-scale

0.515

High

928225

SUMO1
Small ubiquitin-related modifier 1

1

1

Small-scale

0.515

High

396008

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.501

High

435186

SP1
Transcription factor Sp1

1

11

Small-scale

0.501

High

1137455

MCAF2
Activating transcription factor 7-interacting protein 2

1

1

Small-scale

0.501

High

1069093

Q15156
PML-RAR protein

1

20

Small-scale

0.500

High

254238

MEGF6
Multiple epidermal growth factor-like domains protein 6

1

5

High-throughput

0.494

High

624338

TENA
Tenascin

1

3

High-throughput

0.494

High

883202

HUNK
Hormonally up-regulated neu tumor-associated kinase

1

3

High-throughput

0.494

High

1231808

LTBP4
Latent-transforming growth factor beta-binding protein 4

1

6

High-throughput

0.494

High

1271536

NELL1
Protein kinase C-binding protein NELL1

1

7

High-throughput

0.494

High

1295553

CC136
Coiled-coil domain-containing protein 136

1

2

High-throughput

0.494

High

1345280

LTBP3
Latent-transforming growth factor beta-binding protein 3

1

6

High-throughput

0.494

High

1355891

JAG2
Protein jagged-2

1

5

High-throughput

0.494

High

473574

ATX1L
Ataxin-1-like

1

2

High-throughput

0.481

High

1296264

Z512B
Zinc finger protein 512B

1

10

High-throughput

0.481

High

1333792

ECT2
Protein ECT2

1

4

High-throughput

0.481

High

1355889

TEN1
Teneurin-1

1

6

Small-scale

0.481

High

170506

TIF1A
Transcription intermediary factor 1-alpha

1

14

High-throughput

0.479

High

348180

MYC
Myc proto-oncogene protein

1

11

Small-scale

0.479

High

359429

K1C14
Keratin, type I cytoskeletal 14

1

5

Small-scale

0.479

High

396819

S10A8
Protein S100-A8

1

4

Small-scale

0.479

High

488032

RARA
Retinoic acid receptor alpha

1

20

Small-scale

0.479

High

517529

PCNA
Proliferating cell nuclear antigen

1

4

Small-scale

0.479

High

828417

CENPA
Histone H3-like centromeric protein A

1

20

High-throughput

0.479

High

832766

MCM2
DNA replication licensing factor MCM2

1

6

High-throughput

0.479

High

918103

H4
Histone H4

1

10

High-throughput

0.479

High

935349

H31
Histone H3.1

1

20

Small-scale

0.479

High

1281461

FBXW7
F-box/WD repeat-containing protein 7

1

9

High-throughput

0.479

High

1300983

CIC
Protein capicua homolog

1

16

High-throughput

0.479

High

1354778

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.479

High

905226

1433G
14-3-3 protein gamma

1

20

High-throughput

0.437

High

1300475

PRAM
PML-RARA-regulated adapter molecule 1

1

8

Small-scale

0.437

High

1331573

PKHA4
Pleckstrin homology domain-containing family A member 4

1

6

High-throughput

0.437

High

60108

A4QMR6
LOC161527 protein

1

1

High-throughput

0.417

High

1200019

RIMS1
Regulating synaptic membrane exocytosis protein 1

1

1

High-throughput

0.407

High

660750

GRN
Progranulin

1

0

High-throughput

0.282

High

959332

S25A3
Solute carrier family 25 member 3

1

0

High-throughput

0.282

High

1264958

PMGT1
Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1

1

0

High-throughput

0.282

High

574063

LOX12
Polyunsaturated fatty acid lipoxygenase ALOX12

1

0

Small-scale

0.249

Low

473359

CC159
Coiled-coil domain-containing protein 159

1

0

High-throughput

0.238

Low

240240

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

0

High-throughput

0.232

Low

1047305

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024