Interactor 1: LRP6 (O75581)
Low-density lipoprotein receptor-related protein 6 (LRP-6)
Gene: LRP6

Interactor 2: LRP6 (O75581)
Low-density lipoprotein receptor-related protein 6 (LRP-6)
Gene: LRP6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.847

The method score is based on:

Property Details
Experiments 28966723, 21984209, 12897152
Identification Methods affinity chromatography technology, molecular sieving, dynamic light scattering, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains FXa_inhibition~FXa_inhibition, FXa_inhibition~Ldl_recept_a, FXa_inhibition~Ldl_recept_b, Ldl_recept_a~Ldl_recept_a, Ldl_recept_a~Ldl_recept_b, Ldl_recept_b~Ldl_recept_b
Common GO terms GO:0005041 - low-density lipoprotein particle receptor activity
GO:0005102 - signaling receptor binding
GO:0005109 - frizzled binding
GO:0005576 - extracellular region
GO:0005783 - endoplasmic reticulum
and 35 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 1613
Hs

1 1613
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024