Protein: MTG8
Protein CBFA2T1 (Cyclin-D-related protein) (Eight twenty one protein) (Protein ETO) (Protein MTG8) (Zinc finger MYND domain-containing protein 2)

Gene: MTG8, RUNX1T1
Organism: Homo sapiens
Interactions: 129
UniProt ID: Q06455

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006351 - DNA-templated transcription

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1055273

PRD14
PR domain zinc finger protein 14

6

7

High-throughput

0.957

High

216172

MTG8R
Protein CBFA2T2

4

5

Small-scale

0.873

High

270241

MTG16
Protein CBFA2T3

3

5

Small-scale

0.847

High

1055278

PRDM6
Putative histone-lysine N-methyltransferase PRDM6

2

8

High-throughput

0.783

High

1055211

MTG8
Protein CBFA2T1

2

7

Small-scale

0.778

High

278314

NCOR1
Nuclear receptor corepressor 1

8

10

Small-scale

0.754

High

253946

LPXN
Leupaxin

4

2

High-throughput

0.703

High

1055263

HTF4
Transcription factor 12

4

9

Small-scale

0.699

High

587061

ITF2
Transcription factor 4

4

9

High-throughput

0.697

High

1055275

PRD12
PR domain zinc finger protein 12

1

9

High-throughput

0.691

High

1055215

HDAC1
Histone deacetylase 1

4

12

Small-scale

0.676

High

1055245

CPSF7
Cleavage and polyadenylation specificity factor subunit 7

3

1

High-throughput

0.675

High

1055286

TRIM1
Probable E3 ubiquitin-protein ligase MID2

3

3

High-throughput

0.675

High

1055296

NCOR2
Nuclear receptor corepressor 2

3

9

Small-scale

0.672

High

928267

ATN1
Atrophin-1

3

10

Small-scale

0.671

High

1055293

WBP11
WW domain-binding protein 11

3

3

High-throughput

0.667

High

1055261

SIN3A
Paired amphipathic helix protein Sin3a

3

3

Small-scale

0.646

High

1055282

ABI3
ABI gene family member 3

4

1

High-throughput

0.644

High

221120

SPY2
Protein sprouty homolog 2

2

1

High-throughput

0.633

High

893836

MEOX2
Homeobox protein MOX-2

2

6

High-throughput

0.633

High

50899

SYCE3
Synaptonemal complex central element protein 3

2

2

High-throughput

0.628

High

1055272

EGLN1
Egl nine homolog 1

1

2

Small-scale

0.618

High

250238

VINEX
Vinexin

2

2

High-throughput

0.606

High

297797

PIAS2
E3 SUMO-protein ligase PIAS2

2

1

High-throughput

0.606

High

574015

HXB2
Homeobox protein Hox-B2

2

3

High-throughput

0.606

High

1004477

RNF4
E3 ubiquitin-protein ligase RNF4

2

2

High-throughput

0.606

High

1022698

XIAP
E3 ubiquitin-protein ligase XIAP

2

2

High-throughput

0.606

High

1048829

REL
Proto-oncogene c-Rel

2

5

High-throughput

0.606

High

1055214

BIRC2
Baculoviral IAP repeat-containing protein 2

2

2

High-throughput

0.606

High

1055250

RT4I1
NAD(P)H oxidoreductase RTN4IP1, mitochondrial

2

1

High-throughput

0.606

High

1055255

TEKT1
Tektin-1

2

2

High-throughput

0.606

High

1055270

TRI54
Tripartite motif-containing protein 54

2

2

High-throughput

0.606

High

1055283

TFP11
Tuftelin-interacting protein 11

2

1

High-throughput

0.606

High

1055284

LHX3
LIM/homeobox protein Lhx3

2

4

High-throughput

0.606

High

1055294

ARIP4
Helicase ARIP4

2

8

High-throughput

0.606

High

1051357

ZBT16
Zinc finger and BTB domain-containing protein 16

2

0

Small-scale

0.605

High

968891

PRS8
26S proteasome regulatory subunit 8

2

0

High-throughput

0.602

High

1055218

GSE1
Genetic suppressor element 1

2

2

High-throughput

0.590

High

1055276

PRD16
Histone-lysine N-methyltransferase PRDM16

1

0

High-throughput

0.589

High

188253

HDAC3
Histone deacetylase 3

2

12

Small-scale

0.584

High

217080

MS18B
Protein Mis18-beta

2

0

High-throughput

0.580

High

688232

TTP
mRNA decay activator protein ZFP36

2

0

High-throughput

0.580

High

1055232

ZN343
Zinc finger protein 343

2

0

High-throughput

0.580

High

1055246

ZN655
Zinc finger protein 655

2

0

High-throughput

0.580

High

1055249

ZFP90
Zinc finger protein 90 homolog

2

0

High-throughput

0.580

High

1055280

PLS3
Phospholipid scramblase 3

2

0

High-throughput

0.580

High

1055287

CDC23
Cell division cycle protein 23 homolog

2

0

High-throughput

0.580

High

1055240

TRI42
Tripartite motif-containing protein 42

1

6

High-throughput

0.573

High

1055256

CR3L1
Cyclic AMP-responsive element-binding protein 3-like protein 1

1

1

High-throughput

0.573

High

1029808

RUNX1
Runt-related transcription factor 1

2

3

Small-scale

0.571

High

543497

VDR
Vitamin D3 receptor

1

2

Small-scale

0.561

High

1055265

GFI1
Zinc finger protein Gfi-1

1

1

Small-scale

0.561

High

725375

KAP1
cAMP-dependent protein kinase type I-beta regulatory subunit

2

2

High-throughput

0.553

High

1053393

DEUP1
Deuterosome assembly protein 1

2

1

High-throughput

0.553

High

1055217

KT33B
Keratin, type I cuticular Ha3-II

2

1

High-throughput

0.553

High

1055226

KR133
Keratin-associated protein 13-3

2

1

High-throughput

0.553

High

1055235

K1C27
Keratin, type I cytoskeletal 27

2

1

High-throughput

0.553

High

1055251

KRT35
Keratin, type I cuticular Ha5

2

1

High-throughput

0.553

High

1055267

RHG09
Rho GTPase-activating protein 9

2

1

High-throughput

0.553

High

1055268

KIFC3
Kinesin-like protein KIFC3

2

1

High-throughput

0.553

High

1055271

K1C23
Keratin, type I cytoskeletal 23

2

2

High-throughput

0.553

High

1055289

LZTS1
Leucine zipper putative tumor suppressor 1

2

1

High-throughput

0.553

High

1055295

CEP83
Centrosomal protein of 83 kDa

2

2

High-throughput

0.553

High

684982

DNMT1
DNA

1

3

Small-scale

0.552

High

1055262

MINT
Msx2-interacting protein

1

4

Small-scale

0.552

High

1055229

ZMYM4
Zinc finger MYM-type protein 4

1

0

High-throughput

0.549

High

1055220

TAL2
T-cell acute lymphocytic leukemia protein 2

1

13

High-throughput

0.541

High

1055253

NGN1
Neurogenin-1

1

14

High-throughput

0.541

High

1055279

UBQL4
Ubiquilin-4

1

1

High-throughput

0.541

High

1055259

UB2E2
Ubiquitin-conjugating enzyme E2 E2

1

0

Small-scale

0.537

High

1055230

BSPRY
B box and SPRY domain-containing protein

1

2

High-throughput

0.536

High

1055288

TRI33
E3 ubiquitin-protein ligase TRIM33

1

6

Small-scale

0.536

High

568795

KAP2
cAMP-dependent protein kinase type II-alpha regulatory subunit

1

2

Small-scale

0.523

High

1055266

LZTS2
Leucine zipper putative tumor suppressor 2

1

2

High-throughput

0.523

High

1055277

TAF9B
Transcription initiation factor TFIID subunit 9B

1

0

High-throughput

0.518

High

464929

SP1
Transcription factor Sp1

1

3

Small-scale

0.515

High

1055292

TR150
Thyroid hormone receptor-associated protein 3

1

2

High-throughput

0.515

High

1055231

Q6FHY5
MEOX2 protein

1

6

High-throughput

0.515

High

1055239

Q86V38
Atrophin 1

1

6

High-throughput

0.515

High

577429

ETS1
Protein C-ets-1

1

2

Small-scale

0.501

High

911220

IMA5
Importin subunit alpha-5

1

1

Small-scale

0.501

High

1032292

OTUD4
OTU domain-containing protein 4

1

0

High-throughput

0.493

High

1055237

SH3R1
E3 ubiquitin-protein ligase SH3RF1

1

3

High-throughput

0.481

High

1055219

IMB1
Importin subunit beta-1

1

0

Small-scale

0.480

High

227515

SPOP
Speckle-type POZ protein

1

2

High-throughput

0.479

High

587456

TFE2
Transcription factor E2-alpha

1

9

Small-scale

0.479

High

615368

SON
Protein SON

1

1

Small-scale

0.479

High

832697

BCL6
B-cell lymphoma 6 protein

1

1

Small-scale

0.479

High

891483

GSK3B
Glycogen synthase kinase-3 beta

1

3

Small-scale

0.479

High

1055216

CUL3
Cullin-3

1

2

High-throughput

0.479

High

1055221

HIF1A
Hypoxia-inducible factor 1-alpha

1

1

Small-scale

0.479

High

1055252

HDAC2
Histone deacetylase 2

1

12

Small-scale

0.479

High

1055254

FBXW7
F-box/WD repeat-containing protein 7

1

1

Small-scale

0.479

High

1055264

TBX5
T-box transcription factor TBX5

1

1

High-throughput

0.479

High

1055269

HDAC8
Histone deacetylase 8

1

12

Small-scale

0.479

High

1055290

ZN652
Zinc finger protein 652

1

3

Small-scale

0.479

High

1055238

Q7Z783
Protein sprouty homolog 2

1

1

High-throughput

0.470

High

799024

BRCA1
Breast cancer type 1 susceptibility protein

1

0

High-throughput

0.460

High

1055227

ZMAT1
Zinc finger matrin-type protein 1

1

0

High-throughput

0.460

High

127939

PSD11
26S proteasome non-ATPase regulatory subunit 11

1

0

High-throughput

0.458

High

159617

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

0

High-throughput

0.458

High

1054688

SUH
Recombining binding protein suppressor of hairless

1

0

Small-scale

0.458

High

1037098

ID3
DNA-binding protein inhibitor ID-3

1

5

High-throughput

0.457

High

1055260

CI072
Guanine nucleotide exchange factor C9orf72

1

0

Small-scale

0.426

High

1055281

HOME3
Homer protein homolog 3

4

0

High-throughput

0.367

High

1055236

NECA2
N-terminal EF-hand calcium-binding protein 2

4

0

High-throughput

0.365

High

1055241

IHO1
Interactor of HORMAD1 protein 1

3

0

High-throughput

0.352

High

1055247

CBY2
Protein chibby homolog 2

3

0

High-throughput

0.352

High

1055212

BRME1
Break repair meiotic recombinase recruitment factor 1

2

0

High-throughput

0.337

High

1055228

EFHC2
EF-hand domain-containing family member C2

2

0

High-throughput

0.327

High

1033349

CDR2
Cerebellar degeneration-related protein 2

2

0

High-throughput

0.316

High

1055223

KRA62
Keratin-associated protein 6-2

2

0

High-throughput

0.316

High

1055225

KR196
Keratin-associated protein 19-6

2

0

High-throughput

0.316

High

1055233

ATL4
ADAMTS-like protein 4

2

0

High-throughput

0.316

High

1055234

K0408
Uncharacterized protein KIAA0408

2

0

High-throughput

0.316

High

1055242

FAM9A
Protein FAM9A

2

0

High-throughput

0.316

High

1055243

SYCE1
Synaptonemal complex central element protein 1

2

0

High-throughput

0.316

High

1055244

VPS52
Vacuolar protein sorting-associated protein 52 homolog

2

0

High-throughput

0.316

High

1055257

F136A
Protein FAM136A

2

0

High-throughput

0.316

High

1055291

COG6
Conserved oligomeric Golgi complex subunit 6

2

0

High-throughput

0.316

High

286644

STX11
Syntaxin-11

1

0

High-throughput

0.299

High

1055213

EPS8
Epidermal growth factor receptor kinase substrate 8

1

0

High-throughput

0.299

High

1055274

PHS2
Pterin-4-alpha-carbinolamine dehydratase 2

1

0

High-throughput

0.282

High

1055222

INSY1
Inhibitory synaptic factor 1

1

0

High-throughput

0.279

Low

1055224

KRA63
Keratin-associated protein 6-3

1

0

High-throughput

0.268

Low

1055248

CC197
Uncharacterized protein CCDC197

1

0

High-throughput

0.268

Low

1055285

IL19
Interleukin-19

1

0

Small-scale

0.249

Low

1055258

C170L
Cep170-like protein

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025