Interactor 1: LRP6 (O75581)
Low-density lipoprotein receptor-related protein 6 (LRP-6)
Gene: LRP6

Interactor 2: WNT1 (P04628)
Proto-oncogene Wnt-1 (Proto-oncogene Int-1 homolog)
Gene: WNT1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 0.60 0.501

The method score is based on:

Property Details
Experiments 11448771
Identification Methods pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005109 - frizzled binding
GO:0005576 - extracellular region
GO:0005886 - plasma membrane
GO:0009986 - cell surface
GO:0016055 - Wnt signaling pathway
and 5 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 1613
Hs

1 370
+ Mm
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+ Mm
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+ Dm
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+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024