HitPredict

Interactor 1: MYCB2 (O75592)
E3 ubiquitin-protein ligase MYCBP2 (EC 2.3.2.33) (Myc-binding protein 2) (Protein associated with Myc)
Gene: MYCBP2

Interactor 2: FBSP1 (P0C2W1)
F-box/SPRY domain-containing protein 1 (F-box only protein 45) (hFbxo45)
Gene: FBXO45

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 0.60 0.749

The method score is based on:

Property Details
Experiments 25143387, 29997255, 31285543, 19398581, 27173435, 33961781, 24992930
Identification Methods affinity chromatography technology, pull down, two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0016567 - protein ubiquitination
GO:0070936 - protein K48-linked ubiquitination
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 4678
Hs

1 286
+ Mm
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+ Hs
+ Ce
+ Dm
+ Hs
+ Hs
+ Mm
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+ Hs
+ Hs
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024