HitPredict

Interactor 1: MYCB2 (O75592)
E3 ubiquitin-protein ligase MYCBP2 (EC 2.3.2.33) (Myc-binding protein 2) (Protein associated with Myc)
Gene: MYCBP2

Interactor 2: TXNIP (Q9H3M7)
Thioredoxin-interacting protein (Thioredoxin-binding protein 2) (Vitamin D3 up-regulated protein 1)
Gene: TXNIP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 4678 Hs			1 391
+	Hs
		320008 HERC2_HUMAN (704-1143): 1.1e-42: 176: 12.53		TXNIP_HUMAN (1-391): 1.4e-149: 430: 100.00
+	Hs
		319928 HERC2_HUMAN (704-1143): 1.1e-42: 176: 12.53		ARRD4_HUMAN (5-383): 9.16e-123: 362: 43.99
+	Dm
		1366418 HERC2_DROME (719-1148): 7.7e-38: 160: 14.19		Q9VGU4_DROME (9-307): 1.81e-68: 226: 17.95
+	Hs
		62191 HERC2_HUMAN (704-1143): 1.1e-42: 176: 12.53		ARRD5_HUMAN (4-329): 8.29e-59: 196: 16.81