Protein: TF3B
Transcription factor IIIB 90 kDa subunit (TFIIIB90) (hTFIIIB90) (B-related factor 1) (BRF-1) (hBRF) (TAF3B2) (TATA box-binding protein-associated factor, RNA polymerase III, subunit 2)

Gene: TF3B, BRF1
Organism: Homo sapiens
Interactions: 82
UniProt ID: Q92994

Gene Ontology (top 5):
GO:0000126 - transcription factor TFIIIB complex
GO:0000995 - RNA polymerase III general transcription initiation factor activity
GO:0001006 - RNA polymerase III type 3 promoter sequence-specific DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

589904

TBP
TATA-box-binding protein

8

13

Small-scale

0.971

High

864967

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

3

High-throughput

0.691

High

1273558

RPC6
DNA-directed RNA polymerase III subunit RPC6

1

4

High-throughput

0.691

High

1273562

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

5

High-throughput

0.691

High

414350

RB
Retinoblastoma-associated protein

3

3

Small-scale

0.678

High

476144

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

2

1

Small-scale

0.595

High

660155

RBL1
Retinoblastoma-like protein 1

1

3

Small-scale

0.561

High

997134

RBL2
Retinoblastoma-like protein 2

1

3

Small-scale

0.561

High

387240

P53
Cellular tumor antigen p53

2

0

Small-scale

0.559

High

1273561

RNF12
E3 ubiquitin-protein ligase RLIM

1

0

Small-scale

0.554

High

1273557

PHS2
Pterin-4-alpha-carbinolamine dehydratase 2

1

1

High-throughput

0.541

High

169911

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

7

High-throughput

0.536

High

854339

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

1

3

High-throughput

0.536

High

897589

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

3

High-throughput

0.536

High

1273560

RPC5
DNA-directed RNA polymerase III subunit RPC5

1

2

High-throughput

0.536

High

360239

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.513

High

1259485

CLC4C
C-type lectin domain family 4 member C

1

0

High-throughput

0.513

High

1273564

TCF20
Transcription factor 20

1

0

High-throughput

0.513

High

1183492

RHOU
Rho-related GTP-binding protein RhoU

1

5

High-throughput

0.501

High

234843

ACSL4
Long-chain-fatty-acid--CoA ligase 4

1

4

High-throughput

0.489

High

813656

CAPZB
F-actin-capping protein subunit beta

1

1

High-throughput

0.489

High

895697

CXCR4
C-X-C chemokine receptor type 4

1

2

High-throughput

0.489

High

1273553

VPS50
Syndetin

1

1

High-throughput

0.489

High

1273552

DTBP1
Dysbindin

1

0

High-throughput

0.486

High

197069

PRP4
U4/U6 small nuclear ribonucleoprotein Prp4

1

3

Small-scale

0.479

High

210184

PRC1
Protein regulator of cytokinesis 1

1

1

High-throughput

0.479

High

308951

KI20A
Kinesin-like protein KIF20A

1

2

High-throughput

0.479

High

432130

HS90A
Heat shock protein HSP 90-alpha

1

3

Small-scale

0.479

High

582418

NUCL
Nucleolin

1

3

Small-scale

0.479

High

586900

CSK22
Casein kinase II subunit alpha'

1

9

Small-scale

0.479

High

625774

CXCR2
C-X-C chemokine receptor type 2

1

2

Small-scale

0.479

High

643561

PTBP1
Polypyrimidine tract-binding protein 1

1

1

Small-scale

0.479

High

714342

HSP74
Heat shock 70 kDa protein 4

1

3

Small-scale

0.479

High

802169

NOP2
Probable 28S rRNA

1

4

Small-scale

0.479

High

862448

ACLY
ATP-citrate synthase

1

2

Small-scale

0.479

High

902706

SUMO2
Small ubiquitin-related modifier 2

1

1

Small-scale

0.479

High

906891

PRS4
26S proteasome regulatory subunit 4

1

4

Small-scale

0.479

High

934368

CSK21
Casein kinase II subunit alpha

1

8

Small-scale

0.479

High

962264

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

1

Small-scale

0.479

High

1064562

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

4

Small-scale

0.479

High

1072150

PCBP2
Poly(rC)-binding protein 2

1

1

Small-scale

0.479

High

1200986

LUZP1
Leucine zipper protein 1

1

3

Small-scale

0.479

High

1267727

HS105
Heat shock protein 105 kDa

1

3

Small-scale

0.479

High

1273554

UBP28
Ubiquitin carboxyl-terminal hydrolase 28

1

4

Small-scale

0.479

High

1273559

ECT2
Protein ECT2

1

1

High-throughput

0.479

High

1273563

RAI14
Ankycorbin

1

2

Small-scale

0.479

High

1273565

TF3C5
General transcription factor 3C polypeptide 5

1

2

Small-scale

0.479

High

1273566

TF3C3
General transcription factor 3C polypeptide 3

1

4

Small-scale

0.479

High

161427

MYPT1
Protein phosphatase 1 regulatory subunit 12A

1

0

Small-scale

0.458

High

211639

ACTN4
Alpha-actinin-4

1

0

Small-scale

0.458

High

396780

S10A8
Protein S100-A8

1

0

Small-scale

0.458

High

455730

PARP1
Poly [ADP-ribose] polymerase 1

1

0

Small-scale

0.458

High

536960

TRI27
Zinc finger protein RFP

1

0

Small-scale

0.458

High

559876

H12
Histone H1.2

1

0

Small-scale

0.458

High

657635

ITPI2
Protein ITPRID2

1

0

Small-scale

0.458

High

946584

DCD
Dermcidin

1

0

Small-scale

0.458

High

1023212

FLII
Protein flightless-1 homolog

1

0

Small-scale

0.458

High

1061034

NOLC1
Nucleolar and coiled-body phosphoprotein 1

1

0

Small-scale

0.458

High

1066489

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

1103951

LRRF1
Leucine-rich repeat flightless-interacting protein 1

1

0

Small-scale

0.458

High

1170129

FA83H
Protein FAM83H

1

0

Small-scale

0.458

High

1183002

SND1
Staphylococcal nuclease domain-containing protein 1

1

0

Small-scale

0.458

High

1240904

SERB1
SERPINE1 mRNA-binding protein 1

1

0

Small-scale

0.458

High

1268527

PXDN
Peroxidasin homolog

1

0

Small-scale

0.458

High

1273555

NEB2
Neurabin-2

1

0

Small-scale

0.458

High

1273556

ZN649
Zinc finger protein 649

1

0

Small-scale

0.458

High

395389

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.457

High

484465

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

1

5

High-throughput

0.445

High

261305

FLNB
Filamin-B

1

1

Small-scale

0.437

High

321611

AP2A1
AP-2 complex subunit alpha-1

1

3

Small-scale

0.437

High

344540

A2MG
Alpha-2-macroglobulin

1

1

Small-scale

0.437

High

398564

PPB1
Alkaline phosphatase, placental type

1

2

Small-scale

0.437

High

456429

PPBI
Intestinal-type alkaline phosphatase

1

2

Small-scale

0.437

High

469879

CO4A
Complement C4-A

1

1

Small-scale

0.437

High

474838

POTEI
POTE ankyrin domain family member I

1

2

Small-scale

0.437

High

1025327

LIPA1
Liprin-alpha-1

1

1

Small-scale

0.437

High

1085023

DREB
Drebrin

1

1

Small-scale

0.437

High

1171097

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

1134256

LRAD1
Low-density lipoprotein receptor class A domain-containing protein 1

1

0

High-throughput

0.279

Low

129812

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

0

High-throughput

0.249

Low

980306

K1C17
Keratin, type I cytoskeletal 17

1

0

Small-scale

0.249

Low

1217878

MISP
Mitotic interactor and substrate of PLK1

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024