HitPredict

Interactor 1: UBP2 (O75604)
Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.4.19.12) (41 kDa ubiquitin-specific protease) (Deubiquitinating enzyme 2) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2)
Gene: USP2

Interactor 2: KRT35 (Q92764)
Keratin, type I cuticular Ha5 (Hair keratin, type I Ha5) (Keratin-35) (K35)
Gene: KRT35

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.50	0.553

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 605 Hs			1 455
+	Hs
		271003 UBP2_HUMAN (1-605): 0: 636: 100.00		KRT34_HUMAN (48-429): 5.17e-160: 459: 71.32
+	Hs
		271118 UBP2_HUMAN (1-605): 0: 636: 100.00		K1C40_HUMAN (19-434): 3.02e-149: 433: 60.82
+	Hs
		271029 UBP2_HUMAN (1-605): 0: 636: 100.00		K1C15_HUMAN (96-408): 3.69e-116: 350: 57.96
+	Hs
		271090 UBP2_HUMAN (1-605): 0: 636: 100.00		KT33B_HUMAN (56-450): 1.95e-115: 346: 69.67
+	Hs
		271093 UBP2_HUMAN (1-605): 0: 636: 100.00		K1H1_HUMAN (49-452): 5.82e-72: 234: 70.94
+	Hs
		1149396 UBP21_HUMAN (72-604): 7.31e-131: 396: 33.86		K1C40_HUMAN (19-434): 3.02e-149: 433: 60.82
+	Hs
		531522 UBP36_HUMAN (162-598): 2.8e-102: 336: 27.15		K1C13_HUMAN (91-408): 2.23e-117: 353: 58.93
+	Hs
		777030 UBP8_HUMAN (61-602): 1.91e-124: 395: 28.81		KRT85_HUMAN (2-452): 5.79e-87: 276: 25.96
+	Hs
		280779 UBP8_HUMAN (61-602): 1.91e-124: 395: 28.81		KRT36_HUMAN (1-446): 1.06e-84: 269: 68.39
+	Hs
		1345488 UBP36_HUMAN (162-598): 2.8e-102: 336: 27.15		KRT84_HUMAN (1-453): 3.43e-94: 297: 23.98
+	Hs
		777043 UBP8_HUMAN (61-602): 1.91e-124: 395: 28.81		K1H1_HUMAN (49-452): 5.82e-72: 234: 70.94
+	Hs
		280760 UBP15_HUMAN (451-597): 1.6e-28: 123: 43.92		KRT34_HUMAN (48-429): 5.17e-160: 459: 71.32
+	Hs
		444429 UBP32_HUMAN (540-597): 1.12e-09: 63.9: 46.55		K1C19_HUMAN (89-405): 7.13e-143: 415: 58.04
+	Hs
		445142 UBP15_HUMAN (451-597): 1.6e-28: 123: 43.92		K1C16_HUMAN (93-408): 1.68e-115: 348: 58.86
+	Hs
		1055096 UBP15_HUMAN (451-597): 1.6e-28: 123: 43.92		KT33B_HUMAN (56-450): 1.95e-115: 346: 69.67
+	Hs
		1270318 UBP15_HUMAN (451-597): 1.6e-28: 123: 43.92		KRT35_HUMAN (1-455): 9.49e-97: 300: 100.00
+	Hs
		1055226 UBP15_HUMAN (451-597): 1.6e-28: 123: 43.92		KRT81_HUMAN (6-454): 3.76e-92: 289: 26.20
+	Hs
		943707 UBP15_HUMAN (451-597): 1.6e-28: 123: 43.92		KRT85_HUMAN (2-452): 5.79e-87: 276: 25.96
+	Hs
		86494 UBP15_HUMAN (451-597): 1.6e-28: 123: 43.92		C4AM86_HUMAN (32-455): 3.69e-85: 269: 100.00
+	Hs
		1071455 UBP15_HUMAN (451-597): 1.6e-28: 123: 43.92		K1H1_HUMAN (49-452): 5.82e-72: 234: 70.94