Protein: COBL
Protein cordon-bleu

Gene: COBL
Organism: Homo sapiens
Interactions: 72
UniProt ID: O75128

Gene Ontology (top 5):
GO:0000578 - embryonic axis specification
GO:0001726 - ruffle
GO:0001757 - somite specification
GO:0001843 - neural tube closure
GO:0001889 - liver development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

271143

ACTB
Actin, cytoplasmic 1

3

6

High-throughput

0.861

High

271151

ACTC
Actin, alpha cardiac muscle 1

2

5

High-throughput

0.811

High

271161

ACTBL
Beta-actin-like protein 2

2

6

High-throughput

0.811

High

271189

PACN2
Protein kinase C and casein kinase substrate in neurons protein 2

6

6

High-throughput

0.736

High

271174

PACN1
Protein kinase C and casein kinase substrate in neurons protein 1

5

6

High-throughput

0.717

High

271175

ACTBM
Putative beta-actin-like protein 3

2

6

High-throughput

0.712

High

271188

PACN3
Protein kinase C and casein kinase substrate in neurons protein 3

4

6

High-throughput

0.699

High

271145

ARP2
Actin-related protein 2

1

6

High-throughput

0.691

High

271150

ACTG
Actin, cytoplasmic 2

1

6

High-throughput

0.691

High

271125

WDR47
WD repeat-containing protein 47

2

1

High-throughput

0.628

High

271156

FHL3
Four and a half LIM domains protein 3

3

1

High-throughput

0.609

High

271187

FBW1B
F-box/WD repeat-containing protein 11

2

0

High-throughput

0.602

High

271129

EZRI
Ezrin

2

3

High-throughput

0.584

High

123524

MYO1C
Unconventional myosin-Ic

1

1

High-throughput

0.536

High

271160

DREB
Drebrin

1

1

High-throughput

0.536

High

271169

MY18A
Unconventional myosin-XVIIIa

1

1

High-throughput

0.536

High

271172

MYO19
Unconventional myosin-XIX

1

1

High-throughput

0.536

High

271183

PDLI7
PDZ and LIM domain protein 7

1

2

High-throughput

0.536

High

271185

NLGN3
Neuroligin-3

1

0

High-throughput

0.518

High

271131

FLNA
Filamin-A

1

0

High-throughput

0.513

High

271138

MYH9
Myosin-9

1

0

High-throughput

0.513

High

271139

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

0

High-throughput

0.513

High

271140

CAZA2
F-actin-capping protein subunit alpha-2

1

0

High-throughput

0.513

High

271166

SYNPO
Synaptopodin

1

0

High-throughput

0.513

High

271171

VMP1
Vacuole membrane protein 1

1

0

High-throughput

0.513

High

271182

ANLN
Anillin

1

0

High-throughput

0.513

High

271186

LIMA1
LIM domain and actin-binding protein 1

1

0

High-throughput

0.513

High

271191

AKT3
RAC-gamma serine/threonine-protein kinase

1

0

High-throughput

0.513

High

271158

MARE1
Microtubule-associated protein RP/EB family member 1

1

1

High-throughput

0.489

High

222572

PRC1
Protein regulator of cytokinesis 1

1

1

High-throughput

0.479

High

271134

EPHA2
Ephrin type-A receptor 2

1

1

High-throughput

0.479

High

271136

RADI
Radixin

1

3

High-throughput

0.479

High

271141

GSK3A
Glycogen synthase kinase-3 alpha

1

1

High-throughput

0.479

High

271142

GSK3B
Glycogen synthase kinase-3 beta

1

1

High-throughput

0.479

High

271144

CDC42
Cell division control protein 42 homolog

1

4

High-throughput

0.479

High

271146

1433G
14-3-3 protein gamma

1

9

High-throughput

0.479

High

271148

RHOB
Rho-related GTP-binding protein RhoB

1

3

High-throughput

0.479

High

271149

RAC1
Ras-related C3 botulinum toxin substrate 1

1

3

High-throughput

0.479

High

271153

CAV1
Caveolin-1

1

1

High-throughput

0.479

High

271154

1433F
14-3-3 protein eta

1

9

High-throughput

0.479

High

271159

ZYX
Zyxin

1

1

High-throughput

0.479

High

271163

RHOU
Rho-related GTP-binding protein RhoU

1

4

High-throughput

0.479

High

271179

RHOJ
Rho-related GTP-binding protein RhoJ

1

4

High-throughput

0.479

High

271181

RHOF
Rho-related GTP-binding protein RhoF

1

4

High-throughput

0.479

High

271190

MARE3
Microtubule-associated protein RP/EB family member 3

1

1

High-throughput

0.479

High

271126

RASK
GTPase KRas

1

0

High-throughput

0.458

High

271132

GCSP
Glycine dehydrogenase

1

0

High-throughput

0.458

High

271157

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

271164

ATG9A
Autophagy-related protein 9A

1

0

High-throughput

0.458

High

271178

CHM4B
Charged multivesicular body protein 4b

1

0

High-throughput

0.458

High

271180

ECT2
Protein ECT2

1

0

High-throughput

0.458

High

271135

1433S
14-3-3 protein sigma

1

9

High-throughput

0.437

High

271165

HOOK3
Protein Hook homolog 3

1

3

High-throughput

0.437

High

271192

NINL
Ninein-like protein

1

2

High-throughput

0.437

High

271176

ZDHC5
Palmitoyltransferase ZDHHC5

1

0

High-throughput

0.426

High

271162

PKHA7
Pleckstrin homology domain-containing family A member 7

1

1

High-throughput

0.407

High

271184

TMOD3
Tropomodulin-3

2

0

High-throughput

0.328

High

271128

HEM1
5-aminolevulinate synthase, non-specific, mitochondrial

2

0

High-throughput

0.316

High

271177

RHG39
Rho GTPase-activating protein 39

2

0

High-throughput

0.298

High

271147

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

0

High-throughput

0.279

Low

271152

HTRA4
Serine protease HTRA4

1

0

High-throughput

0.279

Low

271155

EP300
Histone acetyltransferase p300

1

0

High-throughput

0.279

Low

271173

SAHH3
Adenosylhomocysteinase 3

1

0

High-throughput

0.279

Low

128662

MEN1
Menin

1

0

High-throughput

0.249

Low

271127

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low

271130

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

271133

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

271137

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

271167

FBX22
F-box only protein 22

1

0

High-throughput

0.249

Low

271168

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.249

Low

271170

ESR2
Estrogen receptor beta

1

0

High-throughput

0.249

Low

271193

TRRAP
Transformation/transcription domain-associated protein

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025