HitPredict

Interactor 1: OFD1 (O75665)
Centriole and centriolar satellite protein OFD1 (Oral-facial-digital syndrome 1 protein) (Protein 71-7A)
Gene: OFD1

Interactor 2: NDEL1 (Q9GZM8)
Nuclear distribution protein nudE-like 1 (Protein Nudel) (Mitosin-associated protein 1)
Gene: NDEL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005829 - cytosol GO:0043014 - alpha-tubulin binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1012 Hs			1 345
+	Hs
		272738 OFD1_HUMAN (1-1012): 1.82e-122: 400: 100.00		NDE1_HUMAN (3-321): 2.95e-41: 149: 55.25
+	Hs
		272772 OFD1_HUMAN (1-1012): 1.82e-122: 400: 100.00		ICE1_HUMAN (11-277): 4.04e-22: 99.7: 15.83
+	Hs
		1326045 MYO5A_HUMAN (104-658): 3.36e-17: 89.7: 11.88		NDEL1_HUMAN (1-345): 1.8e-67: 217: 100.00
+	Hs
		305120 RIMB1_HUMAN (113-543): 7.41e-30: 130: 15.97		NDE1_HUMAN (3-321): 2.95e-41: 149: 55.25
+	Rn
		222476 MRCKB_RAT (113-627): 1.46e-21: 103: 11.26		MRCKA_RAT (2-209): 6.52e-27: 113: 18.22
+	Hs
		148466 MYH11_HUMAN (19-734): 5.25e-22: 105: 9.38		CTRO_HUMAN (12-211): 2.55e-24: 106: 19.32
+	Hs
		725097 MYH11_HUMAN (19-734): 5.25e-22: 105: 9.38		MYH10_HUMAN (2-228): 6.16e-23: 102: 18.06
+	Rn
		222472 MRCKA_RAT (97-525): 2.81e-17: 89.7: 12.59		MRCKA_RAT (2-209): 6.52e-27: 113: 18.22
+	Hs
		148126 CTRO_HUMAN (97-647): 2.57e-17: 90.1: 15.29		CTRO_HUMAN (12-211): 2.55e-24: 106: 19.32
+	Hs
		148460 CTRO_HUMAN (97-647): 2.57e-17: 90.1: 15.29		MYH9_HUMAN (2-223): 7.48e-24: 105: 17.57
+	Hs
		1137917 MRCKB_HUMAN (116-621): 1.91e-20: 100: 11.58		MRCKA_HUMAN (2-204): 1.99e-20: 94.7: 17.41
+	Hs
		725086 MYO5A_HUMAN (104-658): 3.36e-17: 89.7: 11.88		MYH9_HUMAN (2-223): 7.48e-24: 105: 17.57
+	Hs
		148461 CTRO_HUMAN (97-647): 2.57e-17: 90.1: 15.29		MYH10_HUMAN (2-228): 6.16e-23: 102: 18.06
+	Hs
		148935 CTRO_HUMAN (97-647): 2.57e-17: 90.1: 15.29		CYTSA_HUMAN (2-331): 7.36e-23: 102: 16.06
+	Hs
		724687 MYH10_HUMAN (13-485): 7.3e-15: 82: 11.77		MYH9_HUMAN (2-223): 7.48e-24: 105: 17.57
+	Hs
		725095 MYH10_HUMAN (13-485): 7.3e-15: 82: 11.77		MYH10_HUMAN (2-228): 6.16e-23: 102: 18.06
+	Hs
		1137871 MRCKA_HUMAN (97-525): 3.54e-16: 86.2: 13.05		MRCKA_HUMAN (2-204): 1.99e-20: 94.7: 17.41
+	Hs
		148991 CTRO_HUMAN (97-647): 2.57e-17: 90.1: 15.29		MYH14_HUMAN (2-216): 1.78e-13: 73.5: 19.54