Interactor 1: RENR (O75787)
Renin receptor (ATPase H(+)-transporting lysosomal accessory protein 2) (ATPase H(+)-transporting lysosomal-interacting protein 2) (ER-localized type I transmembrane adapter) (Embryonic liver differentiation factor 10) (N14F) (Renin/prorenin receptor) (Vacuolar ATP synthase membrane sector-associated protein M8-9) (ATP6M8-9) (V-ATPase M8.9 subunit) [Cleaved into: Renin receptor N-terminal fragment; Renin receptor C-terminal fragment]
Gene: ATP6AP2

Interactor 2: RENI (P00797)
Renin (EC 3.4.23.15) (Angiotensinogenase)
Gene: REN

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.57 0.55 0.561

The method score is based on:

Property Details
Experiments 12045255
Identification Methods pull down, biochemical, affinity chromatography technology
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002003 - angiotensin maturation
GO:0005886 - plasma membrane
GO:0043408 - regulation of MAPK cascade
Homologous interactions 0

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Last updated: 15 Jul 2024