HitPredict

Interactor 1: BCAR3 (O75815)
Breast cancer anti-estrogen resistance protein 3 (Novel SH2-containing protein 2) (SH2 domain-containing protein 3B)
Gene: BCAR3

Interactor 2: FUS (P35637)
RNA-binding protein FUS (75 kDa DNA-pairing protein) (Oncogene FUS) (Oncogene TLS) (POMp75) (Translocated in liposarcoma protein)
Gene: FUS

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	32814053, 17353931
Identification Methods	two hybrid array, two hybrid pooling approach, anti bait coimmunoprecipitation, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 825 Hs			1 526
+	Hs
		275530 BCAR3_HUMAN (1-825): 0: 867: 100.00		PABP1_HUMAN (184-382): 3.08e-12: 71.2: 12.44
+	Hs
		726729 GRB2_HUMAN (99-318): 3.63e-50: 177: 19.91		FUS_HUMAN (1-526): 1.99e-39: 152: 100.00
+	Hs
		522960 SRC_HUMAN (33-349): 1.87e-59: 213: 13.95		PABP4_HUMAN (280-379): 4.96e-13: 73.5: 22.00
+	Hs
		516342 SRC_HUMAN (33-349): 1.87e-59: 213: 13.95		PABP1_HUMAN (184-382): 3.08e-12: 71.2: 12.44
+	Hs
		523147 SRC_HUMAN (33-349): 1.87e-59: 213: 13.95		PABP3_HUMAN (275-379): 5.23e-10: 63.9: 19.05
+	Hs
		516450 GRB2_HUMAN (99-318): 3.63e-50: 177: 19.91		PABP1_HUMAN (184-382): 3.08e-12: 71.2: 12.44
+	Dm
		993224 GRAP_DROME (101-318): 1.25e-43: 158: 19.28		Q9W424_DROME (265-407): 1.99e-18: 88.8: 19.61
+	Dm
		993211 GRAP_DROME (101-318): 1.25e-43: 158: 19.28		Q9VUH6_DROME (28-222): 2.25e-09: 62.6: 22.27