HitPredict

Interactor 1: BCAR3 (O75815)
Breast cancer anti-estrogen resistance protein 3 (Novel SH2-containing protein 2) (SH2 domain-containing protein 3B)
Gene: BCAR3

Interactor 2: ARP2 (P61160)
Actin-related protein 2 (Actin-like protein 2)
Gene: ACTR2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17353931
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005925 - focal adhesion GO:0016020 - membrane
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 825 Hs			1 394
+	Hs
		896864 GRB2_HUMAN (99-318): 3.63e-50: 177: 19.91		ARP2_HUMAN (1-394): 0: 815: 100.00
+	Hs
		454818 FGR_HUMAN (24-337): 3.12e-58: 209: 11.91		ACTB_HUMAN (1-388): 0: 574: 46.65
+	Hs
		522893 SRC_HUMAN (33-349): 1.87e-59: 213: 13.95		ACTS_HUMAN (2-388): 0: 569: 46.51
+	Hs
		548675 VAV_HUMAN (10-316): 3.02e-58: 215: 16.33		ACTA_HUMAN (3-388): 0: 567: 45.86
+	Hs
		802547 CRK_HUMAN (143-416): 6.47e-55: 193: 18.63		ACTB_HUMAN (1-388): 0: 574: 46.65
+	Hs
		442804 HCK_HUMAN (23-337): 2.51e-51: 190: 12.09		ACTB_HUMAN (1-388): 0: 574: 46.65
+	Hs
		891671 GRB2_HUMAN (99-318): 3.63e-50: 177: 19.91		ACTB_HUMAN (1-388): 0: 574: 46.65
+	Hs
		924453 GRB2_HUMAN (99-318): 3.63e-50: 177: 19.91		ACTG_HUMAN (3-388): 0: 573: 46.37
+	Hs
		924454 GRB2_HUMAN (99-318): 3.63e-50: 177: 19.91		ACTH_HUMAN (1-388): 0: 569: 45.62
+	Hs
		924456 GRB2_HUMAN (99-318): 3.63e-50: 177: 19.91		ACTC_HUMAN (2-388): 0: 569: 46.51
+	Hs
		666054 SHC1_HUMAN (53-256): 2.41e-37: 150: 23.01		ACTB_HUMAN (1-388): 0: 574: 46.65
+	Hs
		666061 SHC1_HUMAN (53-256): 2.41e-37: 150: 23.01		ACTG_HUMAN (3-388): 0: 573: 46.37
+	Hs
		666062 SHC1_HUMAN (53-256): 2.41e-37: 150: 23.01		ACTS_HUMAN (2-388): 0: 569: 46.51