HitPredict

Interactor 1: PSD10 (O75832)
26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin) (p28(GANK))
Gene: PSMD10

Interactor 2: UCHL5 (Q9Y5K5)
Ubiquitin carboxyl-terminal hydrolase isozyme L5 (UCH-L5) (EC 3.4.19.12) (Ubiquitin C-terminal hydrolase UCH37) (Ubiquitin thioesterase L5)
Gene: UCHL5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.92	0.60	0.746

Property	Details
Experiments	33961781, 35271311, 26186194, 28514442, 34761751, 19615732, 19490896
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 226 Hs			1 329
+	Hs
		883692 RIPK4_HUMAN (10-224): 1.17e-53: 185: 26.39		UCHL5_HUMAN (1-329): 1.1e-175: 491: 100.00
+	Hs
		1330906 Q9H4D1_HUMAN (10-224): 1.95e-53: 184: 26.39		UCHL5_HUMAN (1-329): 1.1e-175: 491: 100.00
+	Hs
		1164393 POTEE_HUMAN (1-125): 1.17e-24: 103: 22.40		UCHL5_HUMAN (1-329): 1.1e-175: 491: 100.00
+	Hs
		60453 POTEF_HUMAN (1-125): 1.39e-24: 103: 22.40		UCHL5_HUMAN (1-329): 1.1e-175: 491: 100.00
+	Hs
		456528 RIPK4_HUMAN (10-224): 1.17e-53: 185: 26.39		UCHL1_HUMAN (10-226): 1.03e-74: 231: 22.22
+	Hs
		456646 Q9H4D1_HUMAN (10-224): 1.95e-53: 184: 26.39		UCHL1_HUMAN (10-226): 1.03e-74: 231: 22.22
+	Sp
		1013749 YD58_SCHPO (19-143): 3.38e-13: 68.2: 34.13		UBLH2_SCHPO (7-325): 1.13e-114: 335: 38.77
+	Hs
		456665 ANKR6_HUMAN (1-95): 1.42e-19: 88.5: 21.05		UCHL1_HUMAN (10-226): 1.03e-74: 231: 22.22
+	Hs
		276199 PSD10_HUMAN (1-226): 8.43e-70: 214: 100.00		BAP1_HUMAN (246-315): 2.11e-16: 82: 34.29
+	Hs
		1021440 ANK3_HUMAN (11-224): 5.98e-60: 205: 29.22		BAP1_HUMAN (246-315): 2.11e-16: 82: 34.29
+	Hs
		1267203 RAI14_HUMAN (1-109): 2.71e-20: 90.8: 23.85		BAP1_HUMAN (246-315): 2.11e-16: 82: 34.29
+	Hs
		161422 MYPT1_HUMAN (146-226): 1.06e-18: 85.9: 30.86		BAP1_HUMAN (246-315): 2.11e-16: 82: 34.29
+	Hs
		257673 ANR17_HUMAN (1-61): 1.78e-10: 62: 19.67		BAP1_HUMAN (246-315): 2.11e-16: 82: 34.29
+	Hs
		1219799 ANKH1_HUMAN (1-61): 4.98e-09: 57.7: 16.39		BAP1_HUMAN (246-315): 2.11e-16: 82: 34.29