HitPredict

Interactor 1: STAM2 (O75886)
Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein)
Gene: STAM2

Interactor 2: PGFRB (P09619)
Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)
Gene: PDGFRB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~SH3_1
Common GO terms	GO:0005737 - cytoplasm GO:0007165 - signal transduction GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 525 Hs			1 1106
+	Hs
		276999 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		PGFRA_HUMAN (3-1106): 0: 716: 42.48
+	Hs
		557217 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		PGFRA_HUMAN (3-1106): 0: 716: 42.48
+	Hs
		277152 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		EPHA6_HUMAN (65-1006): 1.05e-174: 542: 14.44
+	Hs
		277073 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		NTRK3_HUMAN (65-966): 1.49e-133: 427: 16.58
+	Hs
		1081556 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		NTRK3_HUMAN (65-966): 1.49e-133: 427: 16.58
+	Hs
		276996 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		FGFR1_HUMAN (218-720): 1.52e-70: 254: 20.44
+	Hs
		277002 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		FGFR2_HUMAN (9-326): 2.34e-58: 218: 11.51
+	Hs
		1081629 GGA3_HUMAN (1-510): 1.35e-56: 203: 15.73		NTRK3_HUMAN (65-966): 1.49e-133: 427: 16.58
+	Hs
		277004 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		FGFR3_HUMAN (1-313): 7.09e-52: 198: 10.66
+	Hs
		508131 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		FGFR1_HUMAN (218-720): 1.52e-70: 254: 20.44
+	Hs
		601561 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		FGFR2_HUMAN (9-326): 2.34e-58: 218: 11.51
+	Hs
		609455 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		FGFR3_HUMAN (1-313): 7.09e-52: 198: 10.66
+	Hs
		277003 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		FGFR4_HUMAN (200-413): 5.32e-14: 78.7: 17.73
+	Hs
		508257 GGA1_HUMAN (2-516): 8.21e-63: 218: 14.50		FGFR1_HUMAN (218-720): 1.52e-70: 254: 20.44
+	Hs
		508231 GGA3_HUMAN (1-510): 1.35e-56: 203: 15.73		FGFR1_HUMAN (218-720): 1.52e-70: 254: 20.44
+	Hs
		508256 GGA2_HUMAN (2-511): 3.8e-55: 197: 16.80		FGFR1_HUMAN (218-720): 1.52e-70: 254: 20.44
+	Hs
		608072 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		FGFR4_HUMAN (200-413): 5.32e-14: 78.7: 17.73
+	Hs
		601604 GGA3_HUMAN (1-510): 1.35e-56: 203: 15.73		FGFR2_HUMAN (9-326): 2.34e-58: 218: 11.51
+	Hs
		608178 GGA1_HUMAN (2-516): 8.21e-63: 218: 14.50		FGFR4_HUMAN (200-413): 5.32e-14: 78.7: 17.73
+	Hs
		608158 GGA3_HUMAN (1-510): 1.35e-56: 203: 15.73		FGFR4_HUMAN (200-413): 5.32e-14: 78.7: 17.73