HitPredict

Interactor 1: STAM2 (O75886)
Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein)
Gene: STAM2

Interactor 2: PGFRA (P16234)
Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)
Gene: PDGFRA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~SH3_1
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 525 Hs			1 1089
+	Hs
		557217 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		PGFRA_HUMAN (1-1089): 0: 817: 100.00
+	Hs
		276989 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		PGFRB_HUMAN (29-1089): 0: 650: 43.33
+	Hs
		277004 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		FGFR3_HUMAN (745-969): 1.84e-76: 270: 40.74
+	Hs
		277074 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		NTRK2_HUMAN (48-776): 2.93e-51: 197: 14.04
+	Hs
		609455 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		FGFR3_HUMAN (745-969): 1.84e-76: 270: 40.74
+	Hs
		277002 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		FGFR2_HUMAN (6-339): 9.02e-49: 189: 14.90
+	Hs
		601561 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		FGFR2_HUMAN (6-339): 9.02e-49: 189: 14.90
+	Hs
		276988 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		RET_HUMAN (573-690): 7.85e-22: 104: 43.22
+	Hs
		277003 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		FGFR4_HUMAN (3-221): 4.21e-22: 104: 8.36
+	Hs
		276996 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		FGFR1_HUMAN (3-177): 1.39e-14: 80.7: 10.71
+	Hs
		277073 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		NTRK3_HUMAN (28-227): 3.23e-13: 76.1: 9.01
+	Hs
		608072 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		FGFR4_HUMAN (3-221): 4.21e-22: 104: 8.36
+	Hs
		508131 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		FGFR1_HUMAN (3-177): 1.39e-14: 80.7: 10.71
+	Hs
		1081556 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		NTRK3_HUMAN (28-227): 3.23e-13: 76.1: 9.01
+	Hs
		601604 GGA3_HUMAN (1-510): 1.35e-56: 203: 15.73		FGFR2_HUMAN (6-339): 9.02e-49: 189: 14.90
+	Hs
		608178 GGA1_HUMAN (2-516): 8.21e-63: 218: 14.50		FGFR4_HUMAN (3-221): 4.21e-22: 104: 8.36
+	Hs
		434297 GGA3_HUMAN (1-510): 1.35e-56: 203: 15.73		RET_HUMAN (573-690): 7.85e-22: 104: 43.22
+	Hs
		608158 GGA3_HUMAN (1-510): 1.35e-56: 203: 15.73		FGFR4_HUMAN (3-221): 4.21e-22: 104: 8.36
+	Hs
		508257 GGA1_HUMAN (2-516): 8.21e-63: 218: 14.50		FGFR1_HUMAN (3-177): 1.39e-14: 80.7: 10.71
+	Hs
		508231 GGA3_HUMAN (1-510): 1.35e-56: 203: 15.73		FGFR1_HUMAN (3-177): 1.39e-14: 80.7: 10.71