Protein: ENTP6
Ectonucleoside triphosphate diphosphohydrolase 6 (NTPDase 6) (EC 3.6.1.6) (CD39 antigen-like 2)

Gene: ENTP6, ENTPD6
Organism: Homo sapiens
Interactions: 71
UniProt ID: O75354

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0004382 - GDP phosphatase activity
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005794 - Golgi apparatus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

277013

PON2
Serum paraoxonase/arylesterase 2

3

0

High-throughput

0.638

High

277046

GGT7
Glutathione hydrolase 7

2

1

High-throughput

0.628

High

276986

DRA
HLA class II histocompatibility antigen, DR alpha chain

2

5

High-throughput

0.601

High

276997

ACHB2
Neuronal acetylcholine receptor subunit beta-2

2

6

High-throughput

0.601

High

277002

ACHA4
Neuronal acetylcholine receptor subunit alpha-4

2

4

High-throughput

0.601

High

276999

CALX
Calnexin

3

2

High-throughput

0.593

High

277020

NPSR1
Neuropeptide S receptor

1

1

High-throughput

0.541

High

276987

CD1A
T-cell surface glycoprotein CD1a

1

10

High-throughput

0.536

High

276991

LYAG
Lysosomal alpha-glucosidase

1

2

High-throughput

0.536

High

276993

PSPC
Surfactant protein C

1

1

High-throughput

0.536

High

276994

PRG2
Bone marrow proteoglycan

1

2

High-throughput

0.536

High

276995

PGFRA
Platelet-derived growth factor receptor alpha

1

2

High-throughput

0.536

High

276996

HLAG
HLA class I histocompatibility antigen, alpha chain G

1

2

High-throughput

0.536

High

277000

CD1B
T-cell surface glycoprotein CD1b

1

10

High-throughput

0.536

High

277011

SG2A2
Mammaglobin-A

1

1

High-throughput

0.536

High

277012

PTC1
Protein patched homolog 1

1

1

High-throughput

0.536

High

277018

NCEH1
Neutral cholesterol ester hydrolase 1

1

1

High-throughput

0.536

High

277019

BRID5
BRICHOS domain-containing protein 5

1

1

High-throughput

0.536

High

277032

T106A
Transmembrane protein 106A

1

2

High-throughput

0.536

High

277035

ASIC4
Acid-sensing ion channel 4

1

2

High-throughput

0.536

High

277041

CBLN4
Cerebellin-4

1

2

High-throughput

0.536

High

277045

BTNL2
Butyrophilin-like protein 2

1

1

High-throughput

0.536

High

231288

EFNA2
Ephrin-A2

1

0

High-throughput

0.513

High

276984

APOM
Apolipoprotein M

1

0

High-throughput

0.513

High

276985

LY86
Lymphocyte antigen 86

1

0

High-throughput

0.513

High

276998

RAB5A
Ras-related protein Rab-5A

1

0

High-throughput

0.513

High

277007

ACTA
Actin, aortic smooth muscle

1

0

High-throughput

0.513

High

277010

ACTN3
Alpha-actinin-3

1

0

High-throughput

0.513

High

277031

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

8

High-throughput

0.489

High

277040

SDF2L
Stromal cell-derived factor 2-like protein 1

1

1

High-throughput

0.489

High

277003

GSK3B
Glycogen synthase kinase-3 beta

1

0

High-throughput

0.486

High

217608

TGON2
Trans-Golgi network integral membrane protein 2

1

2

High-throughput

0.479

High

277030

5HT3C
5-hydroxytryptamine receptor 3C

1

5

High-throughput

0.479

High

126032

AP3B1
AP-3 complex subunit beta-1

1

0

High-throughput

0.458

High

273461

DJC13
DnaJ homolog subfamily C member 13

1

0

High-throughput

0.458

High

277017

SUSD4
Sushi domain-containing protein 4

1

0

High-throughput

0.458

High

277022

TMM25
Transmembrane protein 25

1

0

High-throughput

0.458

High

277024

PLD6
Mitochondrial cardiolipin hydrolase

1

0

High-throughput

0.458

High

277028

CANT1
Soluble calcium-activated nucleotidase 1

1

0

High-throughput

0.458

High

277039

SIAE
Sialate O-acetylesterase

1

0

High-throughput

0.458

High

73752

C1T9B
Complement C1q and tumor necrosis factor-related protein 9B

1

1

High-throughput

0.445

High

276989

CEL3A
Chymotrypsin-like elastase family member 3A

1

1

High-throughput

0.445

High

276990

C1T9A
Complement C1q and tumor necrosis factor-related protein 9A

1

1

High-throughput

0.445

High

276992

ACHB
Acetylcholine receptor subunit beta

1

6

High-throughput

0.445

High

277001

ACHA3
Neuronal acetylcholine receptor subunit alpha-3

1

6

High-throughput

0.445

High

277014

MICB
MHC class I polypeptide-related sequence B

1

6

High-throughput

0.445

High

277015

HFE
Hereditary hemochromatosis protein

1

5

High-throughput

0.445

High

277016

S39AC
Zinc transporter ZIP12

1

4

High-throughput

0.445

High

277023

S39AB
Zinc transporter ZIP11

1

4

High-throughput

0.445

High

277027

CLC4C
C-type lectin domain family 4 member C

1

1

High-throughput

0.445

High

277042

SCN3B
Sodium channel regulatory subunit beta-3

1

3

High-throughput

0.445

High

277043

NPCL1
NPC1-like intracellular cholesterol transporter 1

1

1

High-throughput

0.445

High

139158

UPK2
Uroplakin-2

1

0

High-throughput

0.426

High

154781

ISLR
Immunoglobulin superfamily containing leucine-rich repeat protein

1

0

High-throughput

0.426

High

277006

LCN6
Epididymal-specific lipocalin-6

1

0

High-throughput

0.426

High

277009

SLC31
Amino acid transporter heavy chain SLC3A1

1

0

High-throughput

0.426

High

277025

LYPD1
Ly6/PLAUR domain-containing protein 1

1

0

High-throughput

0.426

High

277029

CA054
Uncharacterized protein C1orf54

1

0

High-throughput

0.426

High

277037

MAGT1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1

1

0

High-throughput

0.426

High

170580

CLGN
Calmegin

1

2

High-throughput

0.407

High

277034

SAAL1
Protein SAAL1

1

1

High-throughput

0.407

High

277008

NAAA
N-acylethanolamine-hydrolyzing acid amidase

2

0

High-throughput

0.318

High

277005

SPCS3
Signal peptidase complex subunit 3

2

0

High-throughput

0.313

High

277026

TOIP2
Torsin-1A-interacting protein 2

2

0

High-throughput

0.288

High

277036

RGAP1
Rac GTPase-activating protein 1

1

0

High-throughput

0.279

Low

277044

GPN3
GPN-loop GTPase 3

1

0

High-throughput

0.279

Low

277004

ATX1
Ataxin-1

1

0

High-throughput

0.265

Low

276988

NFM
Neurofilament medium polypeptide

1

0

High-throughput

0.249

Low

277021

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

277033

PLD4
5'-3' exonuclease PLD4

1

0

High-throughput

0.249

Low

277038

IFG15
Torsin-1A-interacting protein 2, isoform IFRG15

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025