HitPredict

Interactor 1: STAM2 (O75886)
Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein)
Gene: STAM2

Interactor 2: RIN1 (Q13671)
Ras and Rab interactor 1 (Ras inhibitor JC99) (Ras interaction/interference protein 1)
Gene: RIN1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.612

Property	Details
Experiments	17403676, 22976291
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007165 - signal transduction GO:0030139 - endocytic vesicle
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 525 Hs			1 783
+	Hs
		1044770 ITSN1_HUMAN (188-414): 1.91e-46: 176: 22.50		RIN1_HUMAN (1-783): 0: 734: 100.00
+	Hs
		1355932 GGA1_HUMAN (2-516): 8.21e-63: 218: 14.50		RABX5_HUMAN (285-630): 4.38e-97: 312: 14.21
+	Hs
		1078842 ITSN1_HUMAN (188-414): 1.91e-46: 176: 22.50		Q6NSK7_HUMAN (9-372): 7.26e-41: 163: 23.75
+	Hs
		275213 GRAP2_HUMAN (175-256): 5.08e-13: 72: 41.46		RIN3_HUMAN (9-369): 5.23e-38: 154: 23.21
+	Hs
		924632 GRB2_HUMAN (207-262): 4.5e-12: 67.4: 52.63		TENS2_HUMAN (4-230): 1.01e-38: 157: 18.60
+	Hs
		69536 B0LPF3_HUMAN (207-262): 4.5e-12: 67.4: 52.63		RIN3_HUMAN (9-369): 5.23e-38: 154: 23.21
+	Hs
		924717 GRB2_HUMAN (207-262): 4.5e-12: 67.4: 52.63		RIN3_HUMAN (9-369): 5.23e-38: 154: 23.21
+	Hs
		181839 GRB2_HUMAN (207-262): 4.5e-12: 67.4: 52.63		SOCS1_HUMAN (49-192): 1.35e-26: 110: 24.32