Interactor 1: GABR2 (O75899)
Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51) (HG20)
Gene: GABBR2

Interactor 2: GABR1 (Q9UBS5)
Gamma-aminobutyric acid type B receptor subunit 1 (GABA-B receptor 1) (GABA-B-R1) (GABA-BR1) (GABABR1) (Gb1)
Gene: GABBR1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.972

The method score is based on:

Property Details
Experiments 26817839, 30971491, 9872316, 24305054, 32555460, 32580208, 32581365, 16724110, 24658140
Identification Methods affinity chromatography technology, two hybrid, molecular sieving, x-ray crystallography, cross-linking study, electron microscopy 3D single particle reconstruction, anti tag coimmunoprecipitation, ubiquitin reconstruction
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains 7tm_3~7tm_3, ANF_receptor~ANF_receptor
Common GO terms GO:0004965 - G protein-coupled GABA receptor activity
GO:0005886 - plasma membrane
GO:0007193 - adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
GO:0007214 - gamma-aminobutyric acid signaling pathway
GO:0038039 - G protein-coupled receptor heterodimeric complex
and 5 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 941
Hs

1 961
+ Mm
+ Rn
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Rn

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024