Protein: TPTE2
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 (EC 3.1.3.67) (Lipid phosphatase TPIP) (TPTE and PTEN homologous inositol lipid phosphatase)

Gene: TPTE2
Organism: Homo sapiens
Interactions: 87
UniProt ID: Q6XPS3

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0005216 - monoatomic ion channel activity
GO:0005737 - cytoplasm
GO:0005789 - endoplasmic reticulum membrane
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1110797

PKD2
Polycystin-2

2

0

High-throughput

0.770

High

939933

TPTE
Putative tyrosine-protein phosphatase TPTE

2

14

High-throughput

0.754

High

702130

ITPI2
Protein ITPRID2

3

1

High-throughput

0.667

High

1251106

SH3G1
Endophilin-A2

3

6

High-throughput

0.667

High

1251116

DIAP3
Protein diaphanous homolog 3

3

2

High-throughput

0.667

High

1251099

HAUS1
HAUS augmin-like complex subunit 1

3

0

High-throughput

0.646

High

298930

DNJB5
DnaJ homolog subfamily B member 5

2

8

High-throughput

0.628

High

507239

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

2

3

High-throughput

0.628

High

1092892

STRN3
Striatin-3

2

8

High-throughput

0.628

High

1153177

HERC1
Probable E3 ubiquitin-protein ligase HERC1

2

13

High-throughput

0.628

High

1251115

STRN4
Striatin-4

2

6

High-throughput

0.628

High

316404

RMP
Unconventional prefoldin RPB5 interactor 1

2

1

High-throughput

0.611

High

1251087

TEDC1
Tubulin epsilon and delta complex protein 1

2

0

High-throughput

0.602

High

1251111

CEP44
Centrosomal protein of 44 kDa

2

0

High-throughput

0.602

High

828385

PEX19
Peroxisomal biogenesis factor 19

2

0

High-throughput

0.585

High

1251094

NU133
Nuclear pore complex protein Nup133

2

0

High-throughput

0.585

High

1068840

IFFO1
Non-homologous end joining factor IFFO1

2

2

High-throughput

0.574

High

1251113

NCK5L
Nck-associated protein 5-like

2

0

High-throughput

0.559

High

1101740

PTK7
Inactive tyrosine-protein kinase 7

1

10

High-throughput

0.541

High

323441

TRI37
E3 ubiquitin-protein ligase TRIM37

1

5

High-throughput

0.536

High

732631

ARRB2
Beta-arrestin-2

1

2

High-throughput

0.536

High

1032343

OTUD4
OTU domain-containing protein 4

1

3

High-throughput

0.536

High

1251093

UBP33
Ubiquitin carboxyl-terminal hydrolase 33

1

9

High-throughput

0.536

High

1251120

DNJB4
DnaJ homolog subfamily B member 4

1

8

High-throughput

0.536

High

1054188

P2R3A
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha

1

0

High-throughput

0.517

High

1052048

CALD1
Caldesmon

1

10

High-throughput

0.515

High

1204922

MTX3
Metaxin-3

1

0

High-throughput

0.513

High

1251091

RHBL4
Rhomboid-related protein 4

1

0

High-throughput

0.513

High

1251102

CK5P3
CDK5 regulatory subunit-associated protein 3

1

0

High-throughput

0.513

High

1251105

HAUS7
HAUS augmin-like complex subunit 7

1

0

High-throughput

0.513

High

1251109

HAUS8
HAUS augmin-like complex subunit 8

1

0

High-throughput

0.513

High

1251119

TFP11
Tuftelin-interacting protein 11

1

0

High-throughput

0.513

High

1251125

TLN1
Talin-1

1

8

High-throughput

0.501

High

710319

EPHA2
Ephrin type-A receptor 2

1

11

High-throughput

0.494

High

1251085

LMTK1
Serine/threonine-protein kinase LMTK1

1

20

High-throughput

0.494

High

1251089

LMTK2
Serine/threonine-protein kinase LMTK2

1

20

High-throughput

0.494

High

799226

BRCA1
Breast cancer type 1 susceptibility protein

1

4

High-throughput

0.481

High

177004

CE290
Centrosomal protein of 290 kDa

1

10

High-throughput

0.479

High

220931

XPOT
Exportin-T

1

6

High-throughput

0.479

High

245484

OPA1
Dynamin-like GTPase OPA1, mitochondrial

1

1

High-throughput

0.479

High

273204

CAND2
Cullin-associated NEDD8-dissociated protein 2

1

9

High-throughput

0.479

High

325898

UBR5
E3 ubiquitin-protein ligase UBR5

1

15

High-throughput

0.479

High

340167

PCNT
Pericentrin

1

9

High-throughput

0.479

High

463600

LYN
Tyrosine-protein kinase Lyn

1

9

Small-scale

0.479

High

539070

UMPS
Uridine 5'-monophosphate synthase

1

2

High-throughput

0.479

High

700912

PSB4
Proteasome subunit beta type-4

1

3

High-throughput

0.479

High

731405

STIP1
Stress-induced-phosphoprotein 1

1

6

High-throughput

0.479

High

934766

TERA
Transitional endoplasmic reticulum ATPase

1

4

High-throughput

0.479

High

944505

GEMI4
Gem-associated protein 4

1

2

High-throughput

0.479

High

957954

RAB14
Ras-related protein Rab-14

1

4

High-throughput

0.479

High

1094357

CSN1
COP9 signalosome complex subunit 1

1

1

High-throughput

0.479

High

1105851

TMED1
Transmembrane emp24 domain-containing protein 1

1

1

High-throughput

0.479

High

1135239

NWD1
NACHT domain- and WD repeat-containing protein 1

1

7

High-throughput

0.479

High

1178589

KIF7
Kinesin-like protein KIF7

1

6

High-throughput

0.479

High

1214935

CCD18
Coiled-coil domain-containing protein 18

1

7

High-throughput

0.479

High

1217469

CE350
Centrosome-associated protein 350

1

5

High-throughput

0.479

High

1251086

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

12

High-throughput

0.479

High

1251088

MIB1
E3 ubiquitin-protein ligase MIB1

1

8

High-throughput

0.479

High

1251090

TBC15
TBC1 domain family member 15

1

1

High-throughput

0.479

High

1251092

IPO4
Importin-4

1

11

High-throughput

0.479

High

1251096

GCN1
Stalled ribosome sensor GCN1

1

15

High-throughput

0.479

High

1251098

VPP1
V-type proton ATPase 116 kDa subunit a 1

1

1

High-throughput

0.479

High

1251104

CK5P2
CDK5 regulatory subunit-associated protein 2

1

11

High-throughput

0.479

High

1251107

AKAP9
A-kinase anchor protein 9

1

10

High-throughput

0.479

High

1251112

UN45A
Protein unc-45 homolog A

1

11

High-throughput

0.479

High

1251118

CEP72
Centrosomal protein of 72 kDa

1

2

High-throughput

0.479

High

1251122

CP131
Centrosomal protein of 131 kDa

1

6

High-throughput

0.479

High

1251123

DICER
Endoribonuclease Dicer

1

7

High-throughput

0.479

High

1251126

CCD61
Centrosomal protein CCDC61

1

1

High-throughput

0.479

High

290048

OFD1
Centriole and centriolar satellite protein OFD1

1

0

High-throughput

0.458

High

1143372

PCM1
Pericentriolar material 1 protein

1

0

High-throughput

0.458

High

1177945

MOONR
Protein moonraker

1

0

High-throughput

0.458

High

1193431

CCD14
Coiled-coil domain-containing protein 14

1

0

High-throughput

0.458

High

1251095

PIBF1
Progesterone-induced-blocking factor 1

1

0

High-throughput

0.458

High

1251124

ADIP
Afadin- and alpha-actinin-binding protein

1

0

High-throughput

0.458

High

126129

AP3B1
AP-3 complex subunit beta-1

1

7

High-throughput

0.437

High

841797

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

5

High-throughput

0.437

High

1060455

DPOE1
DNA polymerase epsilon catalytic subunit A

1

1

High-throughput

0.437

High

1251100

TBC31
TBC1 domain family member 31

1

6

High-throughput

0.437

High

1251108

CCD77
Coiled-coil domain-containing protein 77

1

1

High-throughput

0.437

High

1251110

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

2

High-throughput

0.437

High

1251121

HECD1
E3 ubiquitin-protein ligase HECTD1

1

14

High-throughput

0.437

High

1251097

K0232
Uncharacterized protein KIAA0232

2

0

High-throughput

0.328

High

1251101

KBP
KIF-binding protein

2

0

High-throughput

0.328

High

1251117

RMND1
Required for meiotic nuclear division protein 1 homolog

2

0

High-throughput

0.328

High

1251103

CC138
Coiled-coil domain-containing protein 138

1

0

High-throughput

0.249

Low

1251114

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025