HitPredict

Interactor 1: CCNK (O75909)
Cyclin-K
Gene: CCNK

Interactor 2: RPB1 (P24928)
DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit B1) (EC 2.7.7.6) (3'-5' exoribonuclease) (EC 3.1.13.-) (DNA-directed RNA polymerase II subunit A) (DNA-directed RNA polymerase III largest subunit) (RNA-directed RNA polymerase II subunit RPB1) (EC 2.7.7.48)
Gene: POLR2A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.594

Property	Details
Experiments	9632813, 26659056
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006366 - transcription by RNA polymerase II
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 580 Hs			1 1970
+	Hs
		625007 CCNL2_HUMAN (25-346): 5.1e-73: 244: 24.63		RPB1_HUMAN (1-1611): 0: 1858: 100.00
+	Hs
		236697 CCNT1_HUMAN (14-396): 1.54e-70: 242: 22.25		RPB1_HUMAN (1-1611): 0: 1858: 100.00
+	Hs
		624396 CCNC_HUMAN (16-303): 1.11e-70: 230: 24.07		RPB1_HUMAN (1-1611): 0: 1858: 100.00
+	Hs
		624819 CCNH_HUMAN (41-227): 5.93e-53: 185: 20.31		RPB1_HUMAN (1-1611): 0: 1858: 100.00
+	Sp
		251723 CG1C_SCHPO (16-356): 1.74e-72: 237: 26.80		RPB1_SCHPO (11-1576): 0: 1516: 53.18