HitPredict

Interactor 1: PRAF3 (O75915)
PRA1 family protein 3 (ADP-ribosylation factor-like protein 6-interacting protein 5) (ARL-6-interacting protein 5) (Aip-5) (Cytoskeleton-related vitamin A-responsive protein) (Dermal papilla-derived protein 11) (GTRAP3-18) (Glutamate transporter EAAC1-interacting protein) (JM5) (Prenylated Rab acceptor protein 2) (Protein JWa) (Putative MAPK-activating protein PM27)
Gene: ARL6IP5

Interactor 2: S1PR2 (O95136)
Sphingosine 1-phosphate receptor 2 (S1P receptor 2) (S1P2) (Endothelial differentiation G-protein coupled receptor 5) (Sphingosine 1-phosphate receptor Edg-5) (S1P receptor Edg-5)
Gene: S1PR2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 188 Hs			1 353
+	Hs
		277761 PRAF3_HUMAN (1-188): 9.94e-86: 252: 100.00		LPAR2_HUMAN (18-327): 1.47e-82: 256: 36.00
+	Hs
		277659 PRAF3_HUMAN (1-188): 9.94e-86: 252: 100.00		CNR2_HUMAN (14-316): 2.12e-70: 225: 25.15
+	Hs
		277627 PRAF3_HUMAN (1-188): 9.94e-86: 252: 100.00		S1PR4_HUMAN (13-314): 2.76e-69: 223: 38.39
+	Hs
		277663 PRAF3_HUMAN (1-188): 9.94e-86: 252: 100.00		CCR2_HUMAN (30-311): 3.16e-62: 204: 14.63
+	Hs
		277728 PRAF3_HUMAN (1-188): 9.94e-86: 252: 100.00		LPAR1_HUMAN (18-326): 5.02e-61: 201: 33.33
+	Hs
		242270 PRAF2_HUMAN (2-175): 3.94e-69: 209: 45.40		LPAR1_HUMAN (18-326): 5.02e-61: 201: 33.33