HitPredict

Interactor 1: PRAF3 (O75915)
PRA1 family protein 3 (ADP-ribosylation factor-like protein 6-interacting protein 5) (ARL-6-interacting protein 5) (Aip-5) (Cytoskeleton-related vitamin A-responsive protein) (Dermal papilla-derived protein 11) (GTRAP3-18) (Glutamate transporter EAAC1-interacting protein) (JM5) (Prenylated Rab acceptor protein 2) (Protein JWa) (Putative MAPK-activating protein PM27)
Gene: ARL6IP5

Interactor 2: RAB7A (P51149)
Ras-related protein Rab-7a (EC 3.6.5.2)
Gene: RAB7A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29360040, 34432599
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0015031 - protein transport
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 188 Hs			1 207
+	Hs
		242240 PRAF2_HUMAN (2-175): 3.94e-69: 209: 45.40		RAB1A_HUMAN (1-206): 7.27e-87: 256: 33.50
+	Rn
		192720 PRAF1_RAT (1-139): 8.31e-37: 127: 22.38		RAB1A_RAT (1-206): 7.27e-87: 256: 33.50
+	Hs
		277670 PRAF3_HUMAN (1-188): 9.94e-86: 252: 100.00		RAB5C_HUMAN (9-179): 1.56e-37: 131: 42.44
+	Hs
		918963 PRAF1_HUMAN (1-139): 1.68e-35: 124: 21.68		RAB1A_HUMAN (1-206): 7.27e-87: 256: 33.50
+	Hs
		1328155 PRAF1_HUMAN (1-139): 1.68e-35: 124: 21.68		RAB1B_HUMAN (1-205): 2.14e-86: 255: 34.15
+	Hs
		845332 PRAF1_HUMAN (1-139): 1.68e-35: 124: 21.68		RAB7A_HUMAN (1-207): 5.09e-80: 239: 100.00
+	Hs
		242233 PRAF2_HUMAN (2-175): 3.94e-69: 209: 45.40		RAB5C_HUMAN (9-179): 1.56e-37: 131: 42.44
+	Hs
		845795 PRAF1_HUMAN (1-139): 1.68e-35: 124: 21.68		RAB9A_HUMAN (5-177): 3.51e-68: 209: 56.65
+	Hs
		844785 PRAF1_HUMAN (1-139): 1.68e-35: 124: 21.68		RAB5C_HUMAN (9-179): 1.56e-37: 131: 42.44