Interactor 1: PIAS1 (O75925)
E3 SUMO-protein ligase PIAS1 (EC 2.3.2.-) (DEAD/H box-binding protein 1) (E3 SUMO-protein transferase PIAS1) (Gu-binding protein) (GBP) (Protein inhibitor of activated STAT protein 1) (RNA helicase II-binding protein)
Gene: PIAS1

Interactor 2: SP3 (Q02447)
Transcription factor Sp3 (SPR-2)
Gene: SP3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.46 0.60 0.527

The method score is based on:

Property Details
Experiments 12356736
Identification Methods two hybrid, pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0016605 - PML body
GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 651
Hs

1 781
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024