HitPredict

Interactor 1: FLOT1 (O75955)
Flotillin-1
Gene: FLOT1

Interactor 2: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 36244648
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0035023 - regulation of Rho protein signal transduction
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 427 Hs			1 648
+	Hs
		279406 FLOT1_HUMAN (1-427): 3.27e-145: 421: 100.00		YES_HUMAN (329-607): 1.22e-105: 332: 33.92
+	Hs
		373712 STOM_HUMAN (8-217): 8.04e-21: 93.8: 16.67		RAF1_HUMAN (1-648): 0: 652: 100.00
+	Hs
		522982 FLOT2_HUMAN (4-419): 1.33e-139: 407: 47.61		SRC_HUMAN (331-607): 3.01e-106: 333: 33.45
+	Hs
		433351 FLOT2_HUMAN (4-419): 1.33e-139: 407: 47.61		YES_HUMAN (329-607): 1.22e-105: 332: 33.92
+	Hs
		433259 STOM_HUMAN (8-217): 8.04e-21: 93.8: 16.67		YES_HUMAN (329-607): 1.22e-105: 332: 33.92