HitPredict

Interactor 1: FLOT1 (O75955)
Flotillin-1
Gene: FLOT1

Interactor 2: RAB5C (P51148)
Ras-related protein Rab-5C (EC 3.6.5.2) (L1880) (RAB5L)
Gene: RAB5C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005765 - lysosomal membrane GO:0005768 - endosome GO:0005886 - plasma membrane GO:0042470 - melanosome GO:0070062 - extracellular exosome
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 427 Hs			1 216
+	Hs
		844518 FLOT2_HUMAN (4-419): 1.33e-139: 407: 47.61		RAB5C_HUMAN (1-216): 3.2e-94: 275: 100.00
+	Hs
		279502 FLOT1_HUMAN (1-427): 3.27e-145: 421: 100.00		RB11A_HUMAN (12-216): 7.61e-88: 259: 39.25
+	Hs
		592253 FLOT2_HUMAN (4-419): 1.33e-139: 407: 47.61		RAB5A_HUMAN (1-216): 1.03e-89: 264: 86.57
+	Hs
		914069 FLOT2_HUMAN (4-419): 1.33e-139: 407: 47.61		RB11A_HUMAN (12-216): 7.61e-88: 259: 39.25
+	Dm
		1358745 Q9VWL0_DROME (2-229): 3.77e-22: 98.8: 16.23		RAB5_DROME (2-214): 2.73e-99: 288: 74.65
+	Dm
		185509 Q9VWL0_DROME (2-229): 3.77e-22: 98.8: 16.23		O18332_DROME (12-214): 8.93e-91: 266: 39.22
+	Hs
		844788 STML2_HUMAN (8-217): 5.68e-13: 71.8: 18.48		RAB5C_HUMAN (1-216): 3.2e-94: 275: 100.00
+	Dm
		185649 Q9VWL0_DROME (2-229): 3.77e-22: 98.8: 16.23		RAB6_DROME (16-212): 3.61e-51: 166: 41.12