Protein: NF2L1
Endoplasmic reticulum membrane sensor NFE2L1 (Locus control region-factor 1) (LCR-F1) (Nuclear factor erythroid 2-related factor 1) (NF-E2-related factor 1) (NFE2-related factor 1) (Nuclear factor, erythroid derived 2, like 1) (Protein NRF1, p120 form) (Transcription factor 11) (TCF-11) [Cleaved into: Transcription factor NRF1 (Protein NRF1, p110 form)]

Gene: NF2L1, NFE2L1
Organism: Homo sapiens
Interactions: 46
UniProt ID: Q14494

Gene Ontology (top 5):
GO:0000209 - protein polyubiquitination
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1126872

MAFF
Transcription factor MafF

5

20

Small-scale

0.926

High

193340

MAFG
Transcription factor MafG

4

19

Small-scale

0.882

High

1126850

NF2L1
Endoplasmic reticulum membrane sensor NFE2L1

2

20

High-throughput

0.778

High

1126867

ZHANG
CREB/ATF bZIP transcription factor

2

6

High-throughput

0.778

High

1121398

KEAP1
Kelch-like ECH-associated protein 1

7

10

Small-scale

0.741

High

429885

JUN
Transcription factor Jun

1

19

Small-scale

0.724

High

253407

MAFK
Transcription factor MafK

1

19

High-throughput

0.691

High

370670

FOS
Protein c-Fos

1

20

High-throughput

0.647

High

605255

ATF7
Cyclic AMP-dependent transcription factor ATF-7

1

20

High-throughput

0.647

High

617221

ATF4
Cyclic AMP-dependent transcription factor ATF-4

1

8

High-throughput

0.647

High

1126851

BATF
Basic leucine zipper transcriptional factor ATF-like

1

20

High-throughput

0.647

High

1126852

NFE2
Transcription factor NF-E2 45 kDa subunit

1

20

High-throughput

0.647

High

1126864

BACH2
Transcription regulator protein BACH2

1

18

High-throughput

0.647

High

1126874

NF2L3
Nuclear factor erythroid 2-related factor 3

1

20

High-throughput

0.647

High

1126876

MAFB
Transcription factor MafB

1

20

High-throughput

0.647

High

905404

HCFC1
Host cell factor 1

2

7

Small-scale

0.640

High

1126873

FBW1A
F-box/WD repeat-containing protein 1A

2

20

Small-scale

0.601

High

1126861

FBXW7
F-box/WD repeat-containing protein 7

2

14

Small-scale

0.584

High

891547

GSK3B
Glycogen synthase kinase-3 beta

1

8

Small-scale

0.561

High

279366

TULP3
Tubby-related protein 3

1

1

High-throughput

0.541

High

1121107

UBE4A
Ubiquitin conjugation factor E4 A

1

0

Small-scale

0.537

High

1126868

PARVA
Alpha-parvin

1

0

High-throughput

0.536

High

1126856

WDFY3
WD repeat and FYVE domain-containing protein 3

1

7

High-throughput

0.536

High

1126866

BRD9
Bromodomain-containing protein 9

1

20

High-throughput

0.536

High

1126855

K1C27
Keratin, type I cytoskeletal 27

1

0

High-throughput

0.513

High

1126857

RUSC2
AP-4 complex accessory subunit RUSC2

1

0

High-throughput

0.513

High

1126865

CH033
UPF0488 protein C8orf33

1

1

High-throughput

0.489

High

457092

CAN1
Calpain-1 catalytic subunit

1

1

Small-scale

0.481

High

185694

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

5

Small-scale

0.479

High

322942

UBP19
Ubiquitin carboxyl-terminal hydrolase 19

1

7

Small-scale

0.479

High

372022

MYC
Myc proto-oncogene protein

1

10

High-throughput

0.479

High

572828

NCF1
Neutrophil cytosol factor 1

1

2

Small-scale

0.479

High

1126853

NRF1
Nuclear respiratory factor 1

1

2

Small-scale

0.479

High

1126860

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

13

Small-scale

0.479

High

1126863

PHF12
PHD finger protein 12

1

11

High-throughput

0.479

High

1126869

RNF12
E3 ubiquitin-protein ligase RLIM

1

1

High-throughput

0.479

High

1126870

PRGC1
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha

1

1

Small-scale

0.479

High

1126871

FBW1B
F-box/WD repeat-containing protein 11

1

18

High-throughput

0.479

High

1126875

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

7

Small-scale

0.479

High

1126854

FBX38
F-box only protein 38

1

0

High-throughput

0.458

High

1126858

GATD1
GATA zinc finger domain-containing protein 1

1

0

High-throughput

0.458

High

1056725

FMR1
Fragile X messenger ribonucleoprotein 1

1

6

High-throughput

0.457

High

1126862

CEP63
Centrosomal protein of 63 kDa

1

6

High-throughput

0.457

High

718398

CD6
T-cell differentiation antigen CD6

1

0

High-throughput

0.282

High

1126859

CA054
Uncharacterized protein C1orf54

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025