HitPredict

Interactor 1: FLOT1 (O75955)
Flotillin-1
Gene: FLOT1

Interactor 2: ARHG7 (Q14155)
Rho guanine nucleotide exchange factor 7 (Beta-Pix) (COOL-1) (PAK-interacting exchange factor beta) (p85)
Gene: ARHGEF7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37071682
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005925 - focal adhesion GO:0030027 - lamellipodium
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 427 Hs			1 803
+	Hs
		279427 FLOT1_HUMAN (1-427): 3.27e-145: 421: 100.00		VAV_HUMAN (1-778): 3.84e-111: 360: 16.96
+	Hs
		548705 FLOT2_HUMAN (4-419): 1.33e-139: 407: 47.61		VAV_HUMAN (1-778): 3.84e-111: 360: 16.96
+	Hs
		279771 FLOT1_HUMAN (1-427): 3.27e-145: 421: 100.00		FARP1_HUMAN (225-625): 4.7e-96: 324: 21.36
+	Hs
		279728 FLOT1_HUMAN (1-427): 3.27e-145: 421: 100.00		ARHG4_HUMAN (25-659): 7.11e-98: 320: 19.03
+	Hs
		279667 FLOT1_HUMAN (1-427): 3.27e-145: 421: 100.00		Q96D37_HUMAN (55-778): 3.88e-93: 310: 15.20
+	Dm
		55852 FLOT2_DROME (4-422): 1.58e-141: 413: 42.49		A1ZBA1_DROME (255-794): 3.52e-87: 304: 16.85
+	Hs
		279373 FLOT1_HUMAN (1-427): 3.27e-145: 421: 100.00		TRIO_HUMAN (16-803): 4.74e-74: 266: 13.40
+	Hs
		279570 FLOT1_HUMAN (1-427): 3.27e-145: 421: 100.00		ITSN1_HUMAN (21-245): 9.17e-09: 61.3: 14.68